selinexor

tumor protein p53 ; Homo sapiens







10 Article(s)
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1 35033575 Selinexor improves the anti-cancer effect of tucidinostat on TP53 wild-type breast cancer. 2022 Apr 5 3
2 35217309 Combining selinexor with alisertib to target the p53 pathway in neuroblastoma. 2022 Apr 4
3 33648535 Selinexor versus doxorubicin in dedifferentiated liposarcoma PDXs: evidence of greater activity and apoptotic response dependent on p53 nuclear accumulation and survivin down-regulation. 2021 Mar 1 1
4 34209894 AML-Related NPM Mutations Drive p53 Delocalization into the Cytoplasm with Possible Impact on p53-Dependent Stress Response. 2021 Jun 29 1
5 32045477 Venetoclax response is enhanced by selective inhibitor of nuclear export compounds in hematologic malignancies. 2020 Feb 11 1
6 33148342 XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53. 2020 Nov 4 1
7 30037299 Loss of p53 expression in cancer cells alters cell cycle response after inhibition of exportin-1 but does not prevent cell death. 2018 2
8 30115935 Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor. 2018 Aug 16 3
9 27903750 Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor. 2017 Apr 5
10 26398108 Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program. 2016 Feb 1