tanespimycin

tumor protein p53 ; Homo sapiens







11 Article(s)
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1 30948782 Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells. 2019 Apr 4 1
2 26416354 Sensitization of multidrug-resistant human cancer cells to Hsp90 inhibitors by down-regulation of SIRT1. 2015 Nov 3 3
3 22662219 p53 modulation as a therapeutic strategy in gastrointestinal stromal tumors. 2012 1
4 21478269 Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells. 2011 May 2
5 19956882 p53 independent radio-sensitization of human lymphoblastoid cell lines by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin. 2010 Jan 1
6 20413784 Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury. 2010 Jun 11 3
7 20493187 Geldanamycin and its analog induce cytotoxicity in cultured human retinal pigment epithelial cells. 2010 Aug 1
8 18820127 90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1. 2009 Jan 3
9 17016641 P53-dependent radiosensitizing effects of Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin on human oral squamous cell carcinoma cell lines. 2006 Nov 3
10 17157164 The HSP90 inhibitor 17-AAG synergizes with doxorubicin and U0126 in anaplastic large cell lymphoma irrespective of ALK expression. 2006 Dec 1
11 9622079 Metabolism of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) by murine and human hepatic preparations. 1998 Jun 1 2