Polyamines

tumor protein p53 ; Homo sapiens







18 Article(s)
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1 30842655 p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis. 2019 Mar 1
2 31086338 Publisher Correction: p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis. 2019 May 1
3 29316508 Synthesis and biological evaluation of naphthalimide-polyamine conjugates modified by alkylation as anticancer agents through p53 pathway. 2018 Apr 1
4 27698118 Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses. 2016 Nov 1 2
5 25311224 Lack of functional p53 renders DENSpm-induced autophagy and apoptosis in time dependent manner in colon cancer cells. 2015 Jan 1
6 26835380 Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma. 2015 Jul 1
7 19584241 Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma. 2009 Jul 2
8 17919121 Polyamines modulate the subcellular localization of RNA-binding protein HuR through AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1. 2008 Jan 15 1
9 17442733 p53-dependent NDRG1 expression induces inhibition of intestinal epithelial cell proliferation but not apoptosis after polyamine depletion. 2007 Jul 9
10 17804813 Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells. 2007 Nov 1
11 16690610 Polyamine depletion increases cytoplasmic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs. 2006 Jul 14 5
12 15546879 Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells. 2005 Feb 4 2
13 16131835 Role of p53/p21(Waf1/Cip1) in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells. 2005 Sep 8
14 15180186 Polyamine biosynthesis in relation to K-ras and p-53 mutations in colorectal carcinoma. 2004 May 7
15 10713709 The cytoprotective aminothiol WR1065 activates p21waf-1 and down regulates cell cycle progression through a p53-dependent pathway. 2000 Feb 24 1
16 10096560 Polyamine analogue induction of the p53-p21WAF1/CIP1-Rb pathway and G1 arrest in human melanoma cells. 1999 Mar 15 2
17 10047792 Polyamine analogue-mediated cell cycle responses in human melanoma cells involves the p53, p21, Rb regulatory pathway. 1998 Nov 1
18 8626797 Identification of a region of p53 that confers lability. 1996 Feb 23 1