Tryptophan

tumor protein p53 ; Homo sapiens







48 Article(s)
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1 34958576 Grafting Hydrophobic Amino Acids Critical for Inhibition of Protein-Protein Interactions on a Cell-Penetrating Peptide Scaffold. 2022 Feb 7 1
2 35359247 1H, 15N and 13C backbone resonance assignments of the acidic domain of the human MDMX protein. 2022 Apr 2
3 30419285 Interaction of the anticancer p28 peptide with p53-DBD as studied by fluorescence, FRET, docking and MD simulations. 2019 Feb 1
4 29260852 Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer. 2018 Jan 16 1
5 29853637 Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer. 2018 Jul 20 3
6 28417340 Preconditioning of primary human renal proximal tubular epithelial cells without tryptophan increases survival under hypoxia by inducing autophagy. 2017 Jul 2
7 27291286 Activation of p53 Facilitates the Target Search in DNA by Enhancing the Target Recognition Probability. 2016 Jul 17 1
8 25825738 Autoinhibition of MDMX by intramolecular p53 mimicry. 2015 Apr 14 1
9 25177931 TP53 gene polymorphisms at codons 11, 72, and 248 and association with endometriosis in a Brazilian population. 2014 Aug 26 1
10 22789708 Benzimidazole-2-one: a novel anchoring principle for antagonizing p53-Mdm2. 2013 Jul 15 1
11 22176582 Long-range modulation of chain motions within the intrinsically disordered transactivation domain of tumor suppressor p53. 2012 Jan 25 1
12 21078359 Pea lectin unfolding reveals a unique molten globule fragment chain. 2011 Mar 2
13 22101376 Association of p53 codon 248 (exon7) with urinary bladder cancer risk in the North Indian population. 2011 2
14 20673277 TRP-ing off the p53 apoptotic switch. 2010 Jul 29 1
15 20840120 TRP-ing off the p53 apoptotic switch. 2010 Oct 1
16 20847049 A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53. 2010 Nov 26 3
17 19153082 Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes. 2009 Mar 27 1
18 18193204 Molecular biosensing system based on intrinsically disordered proteins. 2008 Jul 1
19 18707164 Quantum mechanical studies of residue-specific hydrophobic interactions in p53-MDM2 binding. 2008 Sep 11 1
20 18820009 Possible difference in frequencies of genetic polymorphisms of estrogen receptor alpha, estrogen metabolism and P53 genes between estrogen receptor-positive and -negative breast cancers. 2008 Nov 1
21 17371049 Comparison of C40/82A and P27A C40/82A barstar mutants using 19F NMR. 2007 Apr 10 1
22 17508933 Trp/Met/Phe hot spots in protein-protein interactions: potential targets in drug design. 2007 1
23 15571721 Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions? 2005 Jan 14 1
24 15591050 Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence. 2005 Mar 4 3
25 15720190 Small molecule antagonists of the MDM2 oncoprotein as anticancer agents. 2005 Feb 2
26 15780856 Plasma tryptophan during weight restoration in patients with anorexia nervosa. 2005 Mar 15 1
27 16204849 The contribution of the Trp/Met/Phe residues to physical interactions of p53 with cellular proteins. 2005 Jun 2
28 12578368 Surface expansion is independent of and occurs faster than core solvation during the unfolding of barstar. 2003 Feb 18 2
29 12834351 Dynamics of the core tryptophan during the formation of a productive molten globule intermediate of barstar. 2003 Jul 8 1
30 14506283 Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP. 2003 Nov 28 1
31 11594760 p53 unfolding detected by CD but not by tryptophan fluorescence. 2001 Oct 19 2
32 11023067 p53 status and human papillomavirus infection in Thai women with cervical carcinoma. 2000 Mar 1
33 9546285 Frequent inactivation of CDKN2A and rare mutation of TP53 in PCNSL. 1998 Apr 1
34 9740272 K-ras oncogene and p53 gene mutations in cholangiocarcinoma from Thai patients. 1998 Mar 1
35 9801791 Identification of a carbohydrate-binding site in Physarum haemagglutinin I. 1998 Oct 1
36 9825943 Astrocytomas and choroid plexus tumors in two families with identical p53 germline mutations. 1998 Nov 1
37 10069444 P53, p15INK4B, p16INK4A and p57KIP2 mutations during the progression of chronic myeloid leukemia. 1998 1
38 9214306 Folding of tryptophan mutants of barstar: evidence for an initial hydrophobic collapse on the folding pathway. 1997 Jul 15 1
39 9421067 The origin and molecular characterization of adenoid basal carcinoma of the uterine cervix. 1997 Oct 2
40 8810317 Regulation of mutant p53 temperature-sensitive DNA binding. 1996 Oct 11 1
41 8819013 Conformational effects in the p53 protein of mutations induced during chemical carcinogenesis: molecular dynamic and immunologic analyses. 1996 May 2
42 7539102 Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. 1995 Jun 1
43 7784087 Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants. 1995 Jun 15 2
44 7894617 Primary malignant lymphoma of the brain: demonstration of the p53 gene mutations by PCR-SSCP analysis and immunohistochemistry. 1994 1
45 7926727 Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. 1994 May 15 2
46 8290256 Growth suppression of normal mammary epithelial cells by wild-type p53. 1994 Feb 1
47 1466808 Conformational effects of selected cancer-related amino acid substitutions in the p53 protein. 1992 Oct 2
48 1559227 Frequency and diversity of p53 mutations in childhood rhabdomyosarcoma. 1992 Apr 15 1