Flavonoids

tumor protein p53 ; Homo sapiens







27 Article(s)
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1 32715386 A natural flavonoid, apigenin isolated from Clerodendrum viscosum leaves, induces G2/M phase cell cycle arrest and apoptosis in MCF-7 cells through the regulation of p53 and caspase-cascade pathway. 2021 Apr 1
2 33918387 Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line. 2021 Apr 2 1
3 34257824 Role of Dietary Antioxidants in p53-Mediated Cancer Chemoprevention and Tumor Suppression. 2021 1
4 34768743 Bcl-2 Modulation in p53 Signaling Pathway by Flavonoids: A Potential Strategy towards the Treatment of Cancer. 2021 Oct 20 5
5 31278615 FOLFIRI-Mediated Toxicity in Human Aortic Smooth Muscle Cells and Possible Amelioration with Curcumin and Quercetin. 2020 Apr 1
6 32235536 Galangin, a Flavonoid from Lesser Galangal, Induced Apoptosis via p53-Dependent Pathway in Ovarian Cancer Cells. 2020 Mar 30 1
7 32823757 Dietary Flavonoids in p53-Mediated Immune Dysfunctions Linking to Cancer Prevention. 2020 Aug 13 2
8 30661409 Regulation of the Intracellular ROS Level Is Critical for the Antiproliferative Effect of Quercetin in the Hepatocellular Carcinoma Cell Line HepG2. 2019 1
9 31827702 Enhancement of Quercetin-Induced Apoptosis by Cotreatment with Autophagy Inhibitor Is Associated with Augmentation of BAK-Dependent Mitochondrial Pathway in Jurkat T Cells. 2019 1
10 28231749 Flavonoids and Tannins from Smilax china L. Rhizome Induce Apoptosis Via Mitochondrial Pathway and MDM2-p53 Signaling in Human Lung Adenocarcinoma Cells. 2017 4
11 28336971 Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma. 2017 Mar 23 1
12 26706021 Beneficial action of resveratrol: How and why? 2016 Feb 1
13 26089934 The Flavonoid Apigenin Ameliorates Cisplatin-Induced Nephrotoxicity through Reduction of p53 Activation and Promotion of PI3K/Akt Pathway in Human Renal Proximal Tubular Epithelial Cells. 2015 1
14 25026697 Profiling flavonoid cytotoxicity in human breast cancer cell lines: determination of structure-function relationships. 2014 May 1
15 22749133 The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation. 2013 Feb 1
16 21445621 The citrus flavonoid hesperidin induces p53 and inhibits NF-κB activation in order to trigger apoptosis in NALM-6 cells: involvement of PPARγ-dependent mechanism. 2012 Feb 1
17 21915628 Protective effects of flavonoids and extract from Vellozia kolbekii Alves against oxidative stress induced by hydrogen peroxide in yeast. 2012 Apr 1
18 23156993 Profiling flavonoid cytotoxicity in human breast cancer cell lines: determination of structure-function relationships. 2012 Oct 1
19 21479885 Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation. 2011 Dec 1
20 20540768 Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73. 2010 Jun 11 1
21 20858478 The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition. 2010 Dec 15 1
22 18323654 Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cells. 2008 Mar 1
23 18952844 Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage. 2008 Nov 4 3
24 17356895 Caspase-independent death of human osteosarcoma cells by flavonoids is driven by p53-mediated mitochondrial stress and nuclear translocation of AIF and endonuclease G. 2007 Jul 1
25 15795422 (-)Epigallocatechin gallate and quercetin enhance survival signaling in response to oxidant-induced human endothelial apoptosis. 2005 Apr 2
26 12082016 High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter. 2002 Jun 1
27 8895505 Flavonoids activate wild-type p53. 1996 Oct 17 5