memoquin

tumor protein p53 ; Homo sapiens







6 Article(s)
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Pub. Year
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1 33314700 A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death. 2021 Feb 5 1
2 34862374 Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). 2021 Dec 3 2
3 30602570 p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells. 2019 Mar 8 3
4 29670092 APR-246 reactivates mutant p53 by targeting cysteines 124 and 277. 2018 May 1 1
5 26870698 Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer Therapy. 2016 2
6 26086967 APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells. 2015 Jun 18 1