17-(dimethylaminoethylamino)-17-demethoxygeldanamycin

tumor protein p53 ; Homo sapiens







3 Article(s)
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1 21663398 Geldanamycin analog 17-DMAG limits apoptosis in human peripheral blood cells by inhibition of p53 activation and its interaction with heat-shock protein 90 kDa after exposure to ionizing radiation. 2011 Sep 4
2 18025273 Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo. 2007 Nov 3
3 17085670 Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines. 2006 Nov 1 3