Phenylalanine

tumor protein p53 ; Homo sapiens







21 Article(s)
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1 34958576 Grafting Hydrophobic Amino Acids Critical for Inhibition of Protein-Protein Interactions on a Cell-Penetrating Peptide Scaffold. 2022 Feb 7 1
2 35562278 Neurotoxicity of phenylalanine on human iPSC-derived cerebral organoids. 2022 Jun 1
3 33546743 Transcriptomic and metabolomic profiling reveal the p53-dependent benzeneacetic acid attenuation of silica-induced epithelial-mesenchymal transition in human bronchial epithelial cells. 2021 Feb 5 2
4 21280026 Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine. 2011 Jun 1
5 20432447 Cell death of prostate cancer cells by specific amino acid restriction depends on alterations of glucose metabolism. 2010 Aug 3
6 19046801 TP53 mutations in circulating free DNA from Egyptian patients with non-Hodgkin's lymphoma. 2009 Mar 18 2
7 19153082 Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes. 2009 Mar 27 1
8 18707164 Quantum mechanical studies of residue-specific hydrophobic interactions in p53-MDM2 binding. 2008 Sep 11 1
9 17508933 Trp/Met/Phe hot spots in protein-protein interactions: potential targets in drug design. 2007 1
10 16700548 The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol. 2006 May 23 1
11 15591050 Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence. 2005 Mar 4 1
12 16204849 The contribution of the Trp/Met/Phe residues to physical interactions of p53 with cellular proteins. 2005 Jun 2
13 15361841 Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway. 2004 Oct 7 4
14 11925449 The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo. 2002 Aug 9 1
15 10690553 Mismatch repair and p53 independently affect sensitivity to N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea. 2000 Feb 1
16 10611293 The alpha-helical FXXPhiPhi motif in p53: TAF interaction and discrimination by MDM2. 1999 Dec 21 1
17 8819013 Conformational effects in the p53 protein of mutations induced during chemical carcinogenesis: molecular dynamic and immunologic analyses. 1996 May 2
18 7926727 Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. 1994 May 15 1
19 8221663 Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas. 1993 Nov 1 1
20 8325885 Modulation of the human interleukin-6 promoter (IL-6) and transcription factor C/EBP beta (NF-IL6) activity by p53 species. 1993 Jul 15 1
21 1737852 Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia. 1992 Feb 1