Methyl Methanesulfonate

tumor protein p53 ; Homo sapiens







36 Article(s)
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1 32606738 P55PIK Regulates P53-Dependent Apoptosis in Cancer Cells by Interacting with P53 DNA-Specific Domain. 2020 1
2 28195382 Contribution of ATM and ATR kinase pathways to p53-mediated response in etoposide and methyl methanesulfonate induced DNA damage. 2017 Mar 3
3 28347251 Feedback regulation of methyl methanesulfonate and ultraviolet-sensitive gene clone 81 via ATM/Chk2 pathway contributes to the resistance of MCF-7 breast cancer cells to cisplatin. 2017 Mar 1
4 29100281 RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner. 2017 Sep 29 3
5 29107083 p63 and p73 repress CXCR5 chemokine receptor gene expression in p53-deficient MCF-7 breast cancer cells during genotoxic stress. 2017 Dec 1
6 25595616 Acute dosing and p53-deficiency promote cellular sensitivity to DNA methylating agents. 2015 Apr 1
7 23266186 Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase β. 2013 Jan 15 2
8 22405851 p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors. 2012 Jun 1
9 23117069 Methyl methanesulfonate induces apoptosis in p53-deficient H1299 and Hep3B cells through a caspase 2- and mitochondria-associated pathway. 2012 Nov 6
10 19629643 Differential regulation of Apak by various DNA damage signals. 2010 Jan 4
11 20655369 Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro. 2010 Oct 5 1
12 19459735 Enhancement of methyl methanesulfonate-induced base excision repair in the presence of selenomethionine on p53-dependent pathway. 2009 Apr 1
13 15846088 Inhibition of p53 by lentiviral mediated shRNA abrogates G1 arrest and apoptosis in retinal pigmented epithelial cell line. 2005 May 1
14 15388804 Involvement of human p53 in induced intrachromosomal recombination in Saccharomyces cerevisiae. 2004 Sep 1
15 15515172 Comparison of gene expression changes induced in mouse and human cells treated with direct-acting mutagens. 2004 1
16 15665582 The potential roles of p53 tumor suppressor in nucleotide excision repair (NER) and base excision repair (BER). 2004 Dec 31 2
17 17564316 Elimination of methyl methanesulfonate (MMS)-induced micronuclei (MNS) under mild hyperthermia via p53-dependent pathway in human lymphoid cells. 2004 3
18 11890931 SN2 DNA-alkylating agent-induced phosphorylation of p53 and activation of p21 gene expression. 2002 Mar 20 2
19 11223035 Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents. 2001 Feb 16 2
20 11279192 p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents. 2001 May 25 2
21 11375983 Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1. 2001 Aug 10 1
22 11387205 The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis. 2001 Jun 1 1
23 11458984 The effect of methyl methanesulfonate (MMS)-induced excision repair on p53-dependent apoptosis in human lymphoid cells. 2001 Jul 3
24 11494044 DNA alkylation-induced phosphorylation of p53 and activation of kinases in colon cancer cells. 2001 Sep 9
25 10747892 The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression. 2000 Jun 2 1
26 10403664 Methyl methanesulfonate and hydrogen peroxide differentially regulate p53 accumulation in hepatoblastoma cells. 1999 Jun 1 3
27 10435597 The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract. 1999 Jul 15 2
28 10531375 Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. 1999 Oct 29 1
29 10618704 Regulation of p53 in response to DNA damage. 1999 Dec 13 2
30 9271379 Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation. 1997 Sep 1
31 8676920 Characterization of the GADD45 response to ionizing radiation in WI-L2-NS cells, a p53 mutant cell line. 1996 Jun 10 2
32 8892753 Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation. 1996 Oct 1
33 8900110 Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53. 1996 Oct 25 1
34 7478567 The role of the Ataxia telangiectasia gene in the p53, WAF1/CIP1(p21)- and GADD45-mediated response to DNA damage produced by ionising radiation. 1995 Oct 19 1
35 7923116 The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia. 1994 Oct 1 1
36 8321226 Induction of cellular p53 activity by DNA-damaging agents and growth arrest. 1993 Jul 3