| 1 |
35487360 | Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling. | 2022 Aug |
1 |
| 2 |
30802707 | Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2-p53 interaction. | 2019 May |
1 |
| 3 |
30140002 | Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246. | 2018 Aug 23 |
1 |
| 4 |
28710679 | New Phage Display-Isolated Heptapeptide Recognizing the Regulatory Carboxy-Terminal Domain of Human Tumour Protein p53. | 2017 Oct |
1 |
| 5 |
28874603 | Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins. | 2017 Sep 5 |
2 |
| 6 |
27479485 | Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins. | 2016 Sep 21 |
2 |
| 7 |
27601274 | G-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53. | 2016 Sep 7 |
4 |
| 8 |
27735058 | Variation of free-energy landscape of the p53 C-terminal domain induced by acetylation: Enhanced conformational sampling. | 2016 Dec 5 |
1 |
| 9 |
26345853 | Genome-scale meta-analysis of DNA methylation during progression of lung adenocarcinoma. | 2015 Aug 7 |
1 |
| 10 |
25215298 | Involvement of p53 mutation and mismatch repair proteins dysregulation in NNK-induced malignant transformation of human bronchial epithelial cells. | 2014 |
1 |
| 11 |
25221773 | In silico study of fragile histidine triad interaction domains with MDM2 and p53. | 2014 |
3 |
| 12 |
23863845 | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. | 2013 Oct |
2 |
| 13 |
20193843 | Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation. | 2010 Mar |
1 |
| 14 |
18707164 | Quantum mechanical studies of residue-specific hydrophobic interactions in p53-MDM2 binding. | 2008 Sep 11 |
1 |
| 15 |
18717684 | Deletions of BRCA1/2 and p53 R248W gain-of-function mutation suggest impaired homologous recombination repair in fragile histidine triad-negative sebaceous gland carcinomas. | 2008 Dec |
1 |
| 16 |
19127115 | Genetic counseling can influence the course of a suspected familial cancer syndrome patient: from a case of Li-Fraumeni like syndrome with a germline mutation in the TP53 gene. | 2008 Dec |
1 |
| 17 |
16251206 | Sequence specificity of Cr(III)-DNA adduct formation in the p53 gene: NGG sequences are preferential adduct-forming sites. | 2006 Mar |
1 |
| 18 |
15942101 | A patient with TP53 germline mutation developed Bowen's disease and myelodysplastic syndrome with myelofibrosis after chemotherapy against ovarian cancer. | 2005 May |
1 |
| 19 |
16059916 | Exposure to ELF magnetic field tuned to Zn inhibits growth of cancer cells. | 2005 Dec |
5 |
| 20 |
15358233 | Human NTH1 physically interacts with p53 and proliferating cell nuclear antigen. | 2004 Aug 13 |
1 |
| 21 |
12802925 | A novel c-kit positive biphenotypic acute leukemia cell line, TMBL-1, carrying a p53 point mutation. | 2003 May |
1 |
| 22 |
14595027 | Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide. | 2003 Nov 11 |
1 |
| 23 |
11782367 | Activation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. | 2002 Jan 1 |
1 |
| 24 |
11948395 | Characterization of the p53-rescue drug CP-31398 in vitro and in living cells. | 2002 Mar 28 |
1 |
| 25 |
12177781 | Reduced Fhit expression is associated with mismatch repair deficiency in human advanced colorectal carcinoma. | 2002 Aug 12 |
1 |
| 26 |
12200603 | p53 Germline mutation in a patient with Li-Fraumeni Syndrome and three metachronous malignancies. | 2002 Aug |
1 |
| 27 |
11273008 | Second primary glioblastoma. | 2001 Feb |
1 |
| 28 |
11447225 | Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3. | 2001 Sep 28 |
2 |
| 29 |
11527429 | Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka). | 2001 Sep 7 |
1 |
| 30 |
11563689 | Common conformational effects of p53 mutations. | 2001 Feb |
1 |
| 31 |
21340840 | p53 Adenovirus as Gene Therapy for Ovarian Cancer. | 2001 |
1 |
| 32 |
10747932 | Genetic analysis of a potential zinc-binding domain of the adenovirus E4 34k protein. | 2000 May 19 |
1 |
| 33 |
11042688 | Differences in mutant p53 protein stability and functional activity in teniposide-sensitive and -resistant human leukemic CEM cells. | 2000 Oct 12 |
1 |
| 34 |
11097743 | TNF-alpha induced p21(WAF1) but not Bax in colon cancer cells WiDr with mutated p53: important role of protein stabilization. | 2000 Dec |
4 |
| 35 |
10531375 | Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. | 1999 Oct 29 |
1 |
| 36 |
9472015 | High mobility group protein-1 (HMG-1) is a unique activator of p53. | 1998 Feb 15 |
2 |
| 37 |
9581865 | High affinity MAR-DNA binding is a common property of murine and human mutant p53. | 1998 Jun 1 |
2 |
| 38 |
9605749 | Wild-type and mutant forms of p53 activate human topoisomerase I: a possible mechanism for gain of function in mutants. | 1998 May 15 |
3 |
| 39 |
9790785 | Establishment and characterization of a new HPV-negative squamous cell carcinoma cell line (Yumoto) from the human uterine cervix. | 1998 Sep |
1 |
| 40 |
8985102 | Transformation of normal human fibroblasts into immortalized cells with the mutant p53 gene and X-rays. | 1997 Jan 6 |
1 |
| 41 |
9154814 | neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice. | 1997 Jun |
2 |
| 42 |
8649776 | The 273rd codon mutants of p53 show growth modulation activities not correlated with p53-specific transactivation activity. | 1996 Jun 6 |
1 |
| 43 |
8665492 | Studies of the p53 gene mutation in Saudi non-Hodgkin's lymphoma. | 1996 Jul 12 |
1 |
| 44 |
8756655 | A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. | 1996 Sep |
1 |
| 45 |
8810317 | Regulation of mutant p53 temperature-sensitive DNA binding. | 1996 Oct 11 |
2 |
| 46 |
7594817 | Accumulation of mutant p53 and hsp72 by heat treatment, and their association in a human glioblastoma cell line. | 1995 Sep-Oct |
1 |
| 47 |
7627952 | Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53. | 1995 Aug 15 |
1 |
| 48 |
7705936 | Transfected mutant p53 gene increases X-ray-induced cell killing and mutation in human fibroblasts immortalized with 4-nitroquinoline 1-oxide but does not induce neoplastic transformation of the cells. | 1995 Mar 29 |
1 |
| 49 |
7847818 | Mutant p53 proteins behave in a dominant, negative fashion in vivo. | 1994 Sep-Oct |
3 |
| 50 |
7937752 | Conformational effects of environmentally induced, cancer-related mutations in the p53 protein. | 1994 Sep 27 |
1 |