Sulindac

tumor protein p53 ; Homo sapiens







8 Article(s)
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1 27339904 Combined treatment with vitamin C and sulindac synergistically induces p53- and ROS-dependent apoptosis in human colon cancer cells. 2016 Sep 6 2
2 17136320 Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction. 2007 Jan 4
3 16950207 Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin. 2006 Nov 15 3
4 15946692 Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells. 2005 Sep 2 1
5 16273229 Differential gene expression of sulindac-treated human breast epithelial cells. 2005 Dec 3
6 11912124 Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L). 2002 Mar 15 2
7 9192825 Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction. 1997 Jun 15 2
8 8526349 Molecular markers in chemoprevention of colon cancer. Inhibition of expression of ras-p21 and p53 by sulindac during azoxymethane-induced colon carcinogenesis. 1995 Sep 30 1