SAR405838

tumor protein p53 ; Homo sapiens







11 Article(s)
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1 35045964 Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma. 2022 Jan 15 1
2 27550999 Therapeutic Inhibition of the MDM2-p53 Interaction Prevents Recurrence of Adenoid Cystic Carcinomas. 2017 Feb 15 1
3 28324749 A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours. 2017 May 1
4 28498808 Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells. 2017 Jun 27 1
5 26475335 SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma. 2016 Mar 1 4
6 27576846 TP53 mutations emerge with HDM2 inhibitor SAR405838 treatment in de-differentiated liposarcoma. 2016 Aug 31 1
7 27764791 Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma. 2016 Dec 13 5
8 27765850 Reactivation of p53 by MDM2 Inhibitor MI-77301 for the Treatment of Endocrine-Resistant Breast Cancer. 2016 Dec 1
9 25754349 Elucidation of Acquired Resistance to Bcl-2 and MDM2 Inhibitors in Acute Leukemia In Vitro and In Vivo. 2015 Jun 1 2
10 26070072 Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment. 2015 2
11 25145672 SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression. 2014 Oct 15 1