Proline

insulin ; Homo sapiens







64 Article(s)
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1 33369793 A milk casein hydrolysate-derived peptide enhances glucose uptake through the AMP-activated protein kinase signalling pathway in skeletal muscle cells. 2021 Feb 4
2 34560246 Promoting a pro-oxidant state in skeletal muscle: Potential dietary, environmental, and exercise interventions for enhancing endurance-training adaptations. 2021 Nov 20 1
3 32139596 Role of Proinsulin Self-Association in Mutant INS Gene-Induced Diabetes of Youth. 2020 May 1
4 33405562 Insulin-Loaded Silk Fibroin Microneedles as Sustained Release System. 2019 Apr 8 1
5 28598606 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. 2017 Jun 28 2
6 26811873 Modulation of the cellular content of metabolites in adipocytes by insulin. 2016 Mar 15 1
7 27870861 Synergistic Inhibition of Protein Fibrillation by Proline and Sorbitol: Biophysical Investigations. 2016 1
8 23351781 Carbohydrate co-ingestion with protein does not further augment post-prandial muscle protein accretion in older men. 2013 Jan 25 1
9 23416304 Amino acid sequence determinants in self-assembly of insulin chiral amyloid superstructures: role of C-terminus of B-chain in association of fibrils. 2013 Mar 18 1
10 21801810 Neuropeptide Y impairs insulin-stimulated translocation of glucose transporter 4 in 3T3-L1 adipocytes through the Y1 receptor. 2012 Jan 2 1
11 21659604 The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. 2011 Jun 10 1
12 20515662 The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling. 2010 Jul 2 1
13 18991400 High-affinity insulin binding: insulin interacts with two receptor ligand binding sites. 2008 Dec 2 1
14 16631425 Influence of 17beta-estradiol and insulin on type II collagen and protein synthesis of articular chondrocytes. 2006 Aug 2
15 17130464 Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed rats. 2006 Dec 2
16 15486046 Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes. 2005 Feb 1
17 16002803 Co-ingestion of a protein hydrolysate and amino acid mixture with carbohydrate improves plasma glucose disposal in patients with type 2 diabetes. 2005 Jul 1
18 16696315 The influence of the Pro12Ala mutation of PPARgamma2 receptor gene on beta-cells restoration and insulin resistance in type 2 diabetes with hypertension. 2005 1
19 15123681 Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus. 2004 Jul 2 2
20 12716762 The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study. 2003 May 1
21 15526500 Humalog Mix 25 in patients with type 2 diabetes which do not achieve acceptable glycemic control with oral agents: results from a phase III, randomized, parallel study. 2003 1
22 11836319 Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPARgamma gene. 2002 Feb 2
23 12153745 The (ProB27, ThrB28) human insulin analogue is more potent and more rapidly absorbed from subcutis than human insulin. 2002 Aug 1
24 12403639 Insulin lispro: a pharmacoeconomic review of its use in diabetes mellitus. 2002 2
25 11289057 The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences. 2001 Apr 1
26 11334419 Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene. 2001 May 2
27 11524020 Flexibility and bioactivity of insulin: an NMR investigation of the solution structure and folding of an unusually flexible human insulin mutant with increased biological activity. 2001 Sep 4 4
28 11843266 Relationship between plasma cyclo (His-Pro), a neuropeptide common to processed protein-rich food, and C-peptide/insulin molar ratio in obese women. 2001 2
29 11144701 Insulin aspart: a new rapid-acting insulin analog. 2000 Dec 2
30 10051177 Pharmacological management of diabetes: recent progress and future perspective in daily drug treatment. 1999 Jan 1
31 10199158 [Rapid-acting insulin analogues]. 1999 Mar 6
32 10332684 Contribution of postprandial versus interprandial blood glucose to HbA1c in type 1 diabetes on physiologic intensive therapy with lispro insulin at mealtime. 1999 May 1
33 10479347 Preparation of a microcrystalline suspension formulation of Lys(B28)Pro(B29)-human insulin with ultralente properties. 1999 Sep 2
34 10490782 Combination of polymorphisms in OB-R and the OB gene associated with insulin resistance in Nauruan males. 1999 Aug 2
35 9620104 Insulin lispro, a new insulin analog. 1998 May-Jun 1
36 9677011 The human insulin analogue insulin lispro. 1998 Jun 4
37 9708987 Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues. 1998 Aug 18 1
38 9710993 [Spanish experience with insulin lispro]. 1998 Jul 1
39 9088775 Counterregulatory hormone responses and symptoms during hypoglycaemia induced by porcine, human regular insulin, and Lys(B28), Pro(B29) human insulin analogue (insulin Lispro) in healthy male volunteers. 1997 Mar 2
40 9141561 A novel point mutation in the insulin gene giving rise to hyperproinsulinemia. 1997 May 1
41 9248708 Are presently available insulin analogues clinically beneficial? 1997 Jul 2
42 9339963 Insulin lispro: a review of its pharmacological properties and therapeutic use in the management of diabetes mellitus. 1997 Oct 1
43 9374504 Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects. 1997 Nov 28 3
44 9410552 [From the concept of fast acting analogs to the properties of the insulin Lispro]. 1997 Sep 1
45 9428692 Identification of Stat 5B as a substrate of the insulin receptor. 1997 Dec 1 1
46 9434806 Safety and efficacy of [Lys(B28), Pro(B29)]-human insulin in patients with diabetes mellitus. 1997 Nov 1
47 15991899 Insulin lispro: a new quick-acting insulin analogue. 1997 Sep 2
48 8648633 Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin. 1996 Apr 5 1
49 8821525 General pharmacology of insulin lispro in animals. 1996 Jan 1
50 8840095 Prandial glycaemia after a carbohydrate-rich meal in type I diabetic patients: using the rapid acting insulin analogue [Lys(B28), Pro(B29)] human insulin. 1996 Jul 4