| 1 |
35104142 | Molecular Engineering of Efficacious Mono-Valent Ultra-Long Acting Two-Chain Insulin-Fc Conjugates. | 2022 Feb 10 |
2 |
| 2 |
35119848 | Physical Chemistry of a Single tRNA-Modified Nucleoside Regulates Decoding of the Synonymous Lysine Wobble Codon and Affects Type 2 Diabetes. | 2022 Feb 17 |
1 |
| 3 |
32758547 | Lysine-Based Biodegradable Surfactants: Increasing the Lipophilicity of Insulin by Hydrophobic Ion Paring. | 2021 Jan |
1 |
| 4 |
33471541 | Chemoselective and Site-Selective Reductions Catalyzed by a Supramolecular Host and a Pyridine-Borane Cofactor. | 2021 Feb 3 |
1 |
| 5 |
33639734 | Analyzing the driving forces of insulin stability in the basic amino acid solutions: A perspective from hydration dynamics. | 2021 Feb 28 |
4 |
| 6 |
33989998 | Role of surface-exposed charged basic amino acids (Lys, Arg) and guanidination in insulin on the interaction and stability of insulin-insulin receptor complex. | 2021 Jun |
5 |
| 7 |
34723236 | Development and Validation of a Novel LC-MS/MS Assay for C-Peptide in Human Serum. | 2021 Jan |
1 |
| 8 |
30949841 | Identification of Lysine Misincorporation at Asparagine Position in Recombinant Insulin Analogs Produced in E. coli. | 2019 Apr 4 |
3 |
| 9 |
31018989 | Insulin Induces Microtubule Stabilization and Regulates the Microtubule Plus-end Tracking Protein Network in Adipocytes. | 2019 Jul |
1 |
| 10 |
31310433 | Preventive Effects of Thermosensitive Biopolymer-Conjugated C-Peptide against High Glucose-Induced Endothelial Cell Dysfunction. | 2019 Sep |
3 |
| 11 |
29330559 | A post-translational balancing act: the good and the bad of SUMOylation in pancreatic islets. | 2018 Apr |
1 |
| 12 |
29712868 | Insulin promoter in human pancreatic β cells contacts diabetes susceptibility loci and regulates genes affecting insulin metabolism. | 2018 May 15 |
1 |
| 13 |
30094379 | PIAS-family proteins negatively regulate Glis3 transactivation function through SUMO modification in pancreatic β cells. | 2018 Jul |
1 |
| 14 |
28592515 | Intragastric Lysine Lowers the Circulating Glucose and Insulin Responses to a Mixed-Nutrient Drink without Slowing Gastric Emptying in Healthy Adults. | 2017 Jul |
2 |
| 15 |
28853470 | Selective lysine modification of native peptides via aza-Michael addition. | 2017 Sep 13 |
1 |
| 16 |
26847429 | The long-term treatment of a patient with type 1 diabetes mellitus and glutaric aciduria type 1: the effect of insulin. | 2016 Aug |
1 |
| 17 |
27470585 | RKIP phosphorylation-dependent ERK1 activation stimulates adipogenic lipid accumulation in 3T3-L1 preadipocytes overexpressing LC3. | 2016 Sep 9 |
1 |
| 18 |
27581177 | Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers. | 2016 Sep 1 |
2 |
| 19 |
25419905 | Plasma levels of lysine, tyrosine, and valine during pregnancy are independent risk factors of insulin resistance and gestational diabetes. | 2015 Mar |
2 |
| 20 |
25733201 | Effect of insulin sensitizer therapy on amino acids and their metabolites. | 2015 Jun |
1 |
| 21 |
26606380 | Conformational Analysis of the Host-Defense Peptides Pseudhymenochirin-1Pb and -2Pa and Design of Analogues with Insulin-Releasing Activities and Reduced Toxicities. | 2015 Dec 24 |
1 |
| 22 |
24853465 | Can aggregation of insulin govern its fate in the intestine? Implications for oral delivery of the drug. | 2014 Aug 25 |
2 |
| 23 |
23234567 | Conformational memory effect reverses chirality of vortex-induced insulin amyloid superstructures. | 2013 Jan 8 |
1 |
| 24 |
23256662 | Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(ε)ω-carboxyheptadecanoyl) des(B30). | 2013 Jan 15 |
3 |
| 25 |
23416304 | Amino acid sequence determinants in self-assembly of insulin chiral amyloid superstructures: role of C-terminus of B-chain in association of fibrils. | 2013 Mar 18 |
1 |
| 26 |
22291472 | Insulin detemir for the treatment of obese patients with type 2 diabetes. | 2012 |
1 |
| 27 |
22372591 | Effects of oestrogen and testosterone therapy on serum metabolites in postmenopausal women. | 2012 Aug |
1 |
| 28 |
22524975 | The effect of a controlled 8-week metabolic ward based lysine supplementation on muscle function, insulin sensitivity and leucine kinetics in young men. | 2012 Dec |
1 |
| 29 |
22577163 | Proinsulin C-peptide activates α-enolase: implications for C-peptide--cell membrane interaction. | 2012 Jul |
2 |
| 30 |
22942287 | Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity. | 2012 Oct 19 |
1 |
| 31 |
23127165 | Cross-seeding of fibrils from two types of insulin induces new amyloid strains. | 2012 Nov 27 |
2 |
| 32 |
21302286 | Insulin-stimulated L-arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation. | 2011 Nov |
2 |
| 33 |
21708268 | Preparation of monomeric B27 Lys destripeptide insulin by intein mediated expression in Escherichia coli. | 2011 Nov |
4 |
| 34 |
21871446 | Insulin rapidly stimulates L-arginine transport in human aortic endothelial cells via Akt. | 2011 Sep 9 |
1 |
| 35 |
19917601 | Proinsulin C-peptide regulates ribosomal RNA expression. | 2010 Jan 29 |
1 |
| 36 |
18840871 | Comparison of isotope-labeled amino acid incorporation rates (CILAIR) provides a quantitative method to study tissue secretomes. | 2009 Feb |
1 |
| 37 |
19292763 | The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes. | 2009 May |
1 |
| 38 |
19327396 | Insulin induced alteration in post-translational modifications of histone H3 under a hyperglycemic condition in L6 skeletal muscle myoblasts. | 2009 Jun |
1 |
| 39 |
19523989 | Study on preparation and unique properties of a novel insulin analogue with N-terminal Arg-4, Pro-3, Lys-2, Pro-1extension at insulin B-chain. | 2009 Oct 9 |
1 |
| 40 |
19553295 | Lysine ingestion markedly attenuates the glucose response to ingested glucose without a change in insulin response. | 2009 Aug |
3 |
| 41 |
19572292 | Effects of citraconylation on enzymatic modification of human proinsulin using trypsin and carboxypeptidase B. | 2009 Jul-Aug |
8 |
| 42 |
18076215 | Clinical pharmacokinetics and pharmacodynamics of insulin glulisine. | 2008 |
1 |
| 43 |
18491415 | NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer. | 2008 Oct |
1 |
| 44 |
18991400 | High-affinity insulin binding: insulin interacts with two receptor ligand binding sites. | 2008 Dec 2 |
2 |
| 45 |
23055876 | Physical Compatibility of Ibuprofen Lysine Injection with Selected Drugs During Simulated Y-site Injection. | 2008 Jul |
1 |
| 46 |
17703632 | Combining insulins for optimal blood glucose control in type I and 2 diabetes: focus on insulin glulisine. | 2007 |
4 |
| 47 |
17881328 | Pharmacology of insulin detemir. | 2007 Aug |
1 |
| 48 |
17901049 | The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation. | 2007 Nov 23 |
1 |
| 49 |
17901401 | The human insulin gene displays transcriptionally active epigenetic marks in islet-derived mesenchymal precursor cells in the absence of insulin expression. | 2007 Dec |
1 |
| 50 |
16569758 | Decreased nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect. | 2006 Aug |
3 |