Estradiol

hydroxysteroid 17-beta dehydrogenase 7 ; Homo sapiens







65 Article(s)
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1 34873465 An unprecedented endocrine target for ovarian cancer: inhibiting 17β-HSD7 supresses cancer cell proliferation and arrests G2/M cycle. 2021 2
2 31207361 Mutual regulations and breast cancer cell control by steroidogenic enzymes: Dual sex-hormone receptor modulation upon 17β-HSD7 inhibition. 2019 Oct 1
3 29294279 Assessment of the Endocrine-Disrupting Effects of Trichloroethylene and Its Metabolites Using in Vitro and in Silico Approaches. 2018 Feb 6 1
4 28554725 Substrate inhibition of 17β-HSD1 in living cells and regulation of 17β-HSD7 by 17β-HSD1 knockdown. 2017 Sep 1
5 29029113 Estrogen Metabolism in Abdominal Subcutaneous and Visceral Adipose Tissue in Postmenopausal Women. 2017 Dec 1 1
6 23300627 Investigation of testosterone, androstenone, and estradiol metabolism in HepG2 cells and primary culture pig hepatocytes and their effects on 17βHSD7 gene expression. 2012 1
7 21372145 The stimulation of HSD17B7 expression by estradiol provides a powerful feed-forward mechanism for estradiol biosynthesis in breast cancer cells. 2011 May 7
8 19460435 Analysis of 17beta-hydroxysteroid dehydrogenase types 5, 7, and 12 genetic sequence variants in breast cancer cases from French Canadian Families with high risk of breast and ovarian cancer. 2009 Sep 1
9 16166196 Characterization of type 12 17beta-hydroxysteroid dehydrogenase, an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women. 2006 Feb 2
10 16406284 Evaluation of inhibitors for 17beta-hydroxysteroid dehydrogenase type 1 in vivo in immunodeficient mice inoculated with MCF-7 cells stably expressing the recombinant human enzyme. 2006 Mar 27 1
11 16541304 The role of aromatase and 17-beta-hydroxysteroid dehydrogenase type 1 mRNA expression in predicting the clinical outcome of human breast cancer. 2006 Sep 1
12 16755106 New development in intracrinology of breast carcinoma. 2006 3
13 15860265 Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer. 2005 Feb 1
14 15876411 Mammalian lignans and genistein decrease the activities of aromatase and 17beta-hydroxysteroid dehydrogenase in MCF-7 cells. 2005 Apr 1
15 14979917 Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer. 2004 1
16 12917782 Endometriosis: the ultimate hormonal disease. 2003 May 2
17 12943747 Characterisation of estrogenic 17beta-hydroxysteroid dehydrogenase (17beta-HSD) activity in the human brain. 2003 Jul 3
18 11284723 Up-regulation of steroid sulphatase activity in HL60 promyelocytic cells by retinoids and 1alpha,25-dihydroxyvitamin D3. 2001 Apr 15 1
19 11384867 The selective estrogen enzyme modulator (SEEM) in breast cancer. 2001 Jan-Mar 1
20 11443221 The analyses of 17beta-hydroxysteroid dehydrogenase isozymes in human endometrial hyperplasia and carcinoma. 2001 Jul 4
21 11827412 Effect of transforming growth factor-beta1, insulin-like growth factor-I and insulin-like growth factor-II on cell growth and oestrogen metabolism in human breast cancer cell lines. 2001 Nov 1
22 12049480 1-[(Benzofuran-2-yl)phenylmethyl]triazoles as steroidogenic inhibitors: synthesis and in vitro inhibition of human placental CYP19 aromatase. 2001 Aug-Oct 1
23 12227886 Biological effects of progestins in breast cancer. 2001 Dec 1
24 10755407 Direct activation of oestrogen receptor-alpha by interleukin-6 in primary cultures of breast cancer epithelial cells. 2000 Apr 2
25 10824706 The effect of epitestosterone on estrogen biosynthesis in vitro. 2000 Apr 1
26 10536374 Estradiol formation by human osteoblasts via multiple pathways: relation with osteoblast function. 1999 Dec 1 1
27 12227897 Biological effects of progestins in breast cancer. 1999 Jun 1
28 9699877 Progestins and breast cancer. 1998 Apr 1
29 9851796 Deficient 17beta-hydroxysteroid dehydrogenase type 2 expression in endometriosis: failure to metabolize 17beta-estradiol. 1998 Dec 1
30 8994190 Characterization of structural and functional properties of human 17 beta-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis. 1997 Jan 1
31 9275056 1,25-dihydroxyvitamin D3 regulates estrogen metabolism in cultured keratinocytes. 1997 Sep 1
32 9328207 Steroid sulphotransferase and 17beta-hydroxysteroid dehydrogenase activities in Ishikawa human endometrial adenocarcinoma cells. 1997 Apr 1
33 8615688 Polycyclic aromatic hydrocarbon quinone-mediated oxidation reduction cycling catalysed by a human placental 17beta-hydroxysteroid dehydrogenase. 1996 Mar 1 1
34 8615778 Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression. 1996 Mar 15 3
35 8621399 Porcine 80-kDa protein reveals intrinsic 17 beta-hydroxysteroid dehydrogenase, fatty acyl-CoA-hydratase/dehydrogenase, and sterol transfer activities. 1996 Mar 8 1
36 8643647 Localization of 17beta-hydroxysteroid dehydrogenase and characterization of testosterone in the brain of the male frog. 1996 Feb 20 2
37 8729977 17 beta-hydroxysteroid dehydrogenase in common epithelial ovarian tumors. 1996 Apr 1
38 8805577 The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors. 1996 Aug 15 2
39 8938141 Characterization of estrogen-dependent growth of cultured MCF-7 human breast-cancer cells expressing 17beta-hydroxysteroid dehydrogenase type 1. 1996 Nov 27 2
40 8943783 Expression and regulation of 17 beta-hydroxysteroid dehydrogenase type 1. 1996 Sep 1
41 18406737 17beta-Hydroxysteroid dehydrogenase 3 deficiency. 1996 May-Jun 1
42 7546291 The human type II 17 beta-hydroxysteroid dehydrogenase gene encodes two alternatively spliced mRNA species. 1995 Oct 1
43 7626488 Estrone sulfate-sulfatase and 17 beta-hydroxysteroid dehydrogenase activities: a hypothesis for their role in the evolution of human breast cancer from hormone-dependence to hormone-independence. 1995 Jun 1
44 8547177 Role of 17 beta-hydroxysteroid dehydrogenase type 1 in endocrine and intracrine estradiol biosynthesis. 1995 Dec 1
45 8547183 The role and proposed mechanism by which oestradiol 17 beta-hydroxysteroid dehydrogenase regulates breast tumour oestrogen concentrations. 1995 Dec 3
46 8547189 The subcellular localization of 17 beta-hydroxysteroid dehydrogenase type 4 and its interaction with actin. 1995 Dec 1
47 8652148 Regulation of oestrogen action: role of 17 beta-hydroxysteroid dehydrogenases. 1995 Dec 1
48 7525828 Expression of 17 beta-hydroxysteroid dehydrogenase in human granulosa cells: correlation with follicular size, cytochrome P450 aromatase activity and oestradiol production. 1994 Oct 1
49 8239511 Growth factor regulation of 17 beta-hydroxysteroid dehydrogenase activity in a human ovarian cell line: modulation by 17 beta-estradiol. 1993 Sep-Oct 1
50 1580921 Recent data on estrogen sulfatases and sulfotransferases activities in human breast cancer. 1992 Mar 2