Adenosine Triphosphate

hexokinase 2 ; Homo sapiens







27 Article(s)
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1 33811695 Extracellular vesicles regulate purinergic signaling and epithelial sodium channel expression in renal collecting duct cells. 2021 May 2
2 34385105 Panax notoginseng saponins reduces the cisplatin-induced acute renal injury by increasing HIF-1α/BNIP3 to inhibit mitochondrial apoptosis pathway. 2021 Oct 1
3 32859923 Defining the ATPome reveals cross-optimization of metabolic pathways. 2020 Aug 28 3
4 30770778 Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis. 2019 Feb 15 1
5 31270843 Hexokinase2 controls angiogenesis in melanoma by promoting aerobic glycolysis and activating the p38-MAPK signaling. 2019 Dec 5
6 31354221 Hexokinase II promotes the Warburg effect by phosphorylating alpha subunit of pyruvate dehydrogenase. 2019 Jun 1
7 31388064 Identification of alkaline pH optimum of human glucokinase because of ATP-mediated bias correction in outcomes of enzyme assays. 2019 Aug 6 1
8 29423101 Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development. 2018 Jan 9 1
9 29763606 MiR-216a-5p/Hexokinase 2 axis regulates uveal melanoma growth through modulation of Warburg effect. 2018 Jul 2 1
10 29864622 Proteomics analysis demonstrating rosmarinic acid suppresses cell growth by blocking the glycolytic pathway in human HepG2 cells. 2018 Sep 1
11 27544294 In silico construction of HK2-VDAC1 complex and investigating the HK2 binding-induced molecular gating mechanism of VDAC1. 2016 Sep 5
12 27710853 Hyperglycemia induced damage to mitochondrial respiration in renal mesangial and tubular cells: Implications for diabetic nephropathy. 2016 Dec 1
13 25760674 Bisabolane Sesquiterpenoids from the Plant Endophytic Fungus Paraconiothyrium brasiliense. 2015 Apr 24 1
14 26054020 MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer. 2015 Oct 2
15 26324887 p63 supports aerobic respiration through hexokinase II. 2015 Sep 15 2
16 22298254 Up-regulation of hexokinaseII in myeloma cells: targeting myeloma cells with 3-bromopyruvate. 2012 Feb 4
17 22382780 3-Bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective "small molecule" anti-cancer agent taken from labside to bedside: introduction to a special issue. 2012 Feb 1
18 22829728 Comparison and correlation of binding mode of ATP in the kinase domains of Hexokinase family. 2012 1
19 21430642 Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress. 2011 Jun 1
20 21563174 Cyclic 3',5'-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia. 2011 Dec 1 1
21 20800309 Malignant but not naïve hepatocytes of human and rodent origin are killed by TNF after metabolic depletion of ATP by fructose. 2010 Nov 1
22 19101634 Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy. 2009 Feb 1
23 19690031 Evaluation of the role of hexokinase type II in cellular proliferation and apoptosis using human hepatocellular carcinoma cell lines. 2009 Sep 2
24 18535403 Stable RNA interference of hexokinase II gene inhibits human colon cancer LoVo cell growth in vitro and in vivo. 2008 Jul 1
25 16892090 Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria. 2006 Aug 7 2
26 10362817 Calcitriol directly sensitizes renal tubular cells to ATP-depletion- and iron-mediated attack. 1999 Jun 1
27 7883120 Amino acid substitutions in hexokinase II among patients with NIDDM. 1995 Mar 1