Tyrosine

insulin-like growth factor I receptor ; Mus musculus







36 Article(s)
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1 33380522 TrkC Is Essential for Nephron Function and Trans-Activates Igf1R Signaling. 2021 Feb 1
2 30867903 Enriched gestation activates the IGF pathway to evoke embryo-adult benefits to prevent Alzheimer's disease. 2019 1
3 29507819 IGF-I induced phosphorylation of PTH receptor enhances osteoblast to osteocyte transition. 2018 1
4 27609771 Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells. 2016 Oct 1 1
5 26720454 Inhibition of Protein Tyrosine Phosphatase 1B Improves IGF-I Receptor Signaling and Protects Against Inflammation-Induced Gliosis in the Retina. 2015 Dec 1
6 20973552 Design, synthesis, and preclinical evaluation of new 5,6- (or 6,7-) disubstituted-2-(fluorophenyl)quinolin-4-one derivatives as potent antitumor agents. 2010 Nov 25 2
7 19744489 Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy. 2009 Nov 1
8 19744960 GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling. 2009 Dec 1 1
9 17541019 Mechanical stretch simulates proliferation of venous smooth muscle cells through activation of the insulin-like growth factor-1 receptor. 2007 Aug 1
10 17761519 Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. 2007 Dec 1 1
11 14729630 Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. 2004 Jan 1 1
12 14963047 Impaired Shc, Ras, and MAPK activation but normal Akt activation in FL5.12 cells expressing an insulin-like growth factor I receptor mutated at tyrosines 1250 and 1251. 2004 Apr 30 3
13 15500006 Screening for small molecule inhibitors of insulin-like growth factor receptor (IGF-1R) kinase: comparison of homogeneous time-resolved fluorescence and 33P-ATP plate assay formats. 2004 Jul 1
14 12493743 Redundancy of radioresistant signaling pathways originating from insulin-like growth factor I receptor. 2003 Feb 28 2
15 12538620 Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation. 2003 Feb 1
16 12820167 Cre-mediated recombination in the skin melanocyte lineage. 2003 Jun 1
17 12943694 Crosstalk between the extracellular domain of the ErbB2 receptor and IGF-1 receptor signaling. 2003 Jun 1
18 12960377 Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle. 2003 Sep 16 1
19 26680853 The Effects of Insulin-like Growth Factor-I (IGF-I) in Mouse Lung Cancer Cells. 2002 Apr 1
20 10805733 The differential effects of pp120 (Ceacam 1) on the mitogenic action of insulin and insulin-like growth factor 1 are regulated by the nonconserved tyrosine 1316 in the insulin receptor. 2000 Jun 1
21 10847583 The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes. 2000 Jun 1
22 10373346 Increased, not decreased activation of the insulin-like growth factor (IGF) receptor signalling pathway during ceramide-induced apoptosis. 1999 Apr 1
23 10449788 A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide. 1999 Aug 17 1
24 9565625 Insulin-like growth factor-1 (IGF-1) receptor-insulin receptor substrate complexes in the uterus. Altered signaling response to estradiol in the IGF-1(m/m) mouse. 1998 May 8 6
25 9660809 Replacement of tyrosine 1251 in the carboxyl terminus of the insulin-like growth factor-I receptor disrupts the actin cytoskeleton and inhibits proliferation and anchorage-independent growth. 1998 Jul 17 2
26 9165048 Mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways are not sufficient for insulin-like growth factor I-induced mitogenesis and tumorigenesis. 1997 Jun 1
27 9202243 Tyrosine residues in the C-terminal domain of the insulin-like growth factor-I receptor mediate mitogenic and tumorigenic signals. 1997 Jul 1
28 9309326 Ethanol promotes cell death by inhibition of the insulin-like growth factor I receptor. 1997 Sep 2
29 9345292 The tyrosine residue at 1250 of the insulin-like growth factor I receptor is required for ligand-mediated internalization. 1997 Oct 9 5
30 8865975 Ethanol-induced inhibition of cell proliferation is modulated by insulin-like growth factor-I receptor levels. 1996 Aug 2
31 8876252 Estradiol stimulates tyrosine phosphorylation of the insulin-like growth factor-1 receptor and insulin receptor substrate-1 in the uterus. 1996 Oct 15 3
32 8940173 Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src. 1996 Dec 6 4
33 7588225 Single tyrosine substitution in the insulin-like growth factor I receptor inhibits ligand-induced receptor autophosphorylation and internalization, but not mitogenesis. 1995 Nov 4
34 7673254 Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor. 1995 Sep 22 2
35 7512194 Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action. 1994 Jan 1
36 7693688 Structure-function relationship of the insulin-like growth factor-I receptor tyrosine kinase. 1993 Nov 5 1