gemcitabine

MCL1 apoptosis regulator, BCL2 family member ; Homo sapiens







12 Article(s)
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1 34667112 Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL-Specific Degrader DT2216. 2022 Jan 1
2 34156978 MCL1 participates in leptin-promoted mitochondrial fusion and contributes to drug resistance in gallbladder cancer. 2021 Aug 9 2
3 34354046 Gemcitabine and APG-1252, a novel small molecule inhibitor of BCL-2/BCL-XL, display a synergistic antitumor effect in nasopharyngeal carcinoma through the JAK-2/STAT3/MCL-1 signaling pathway. 2021 Aug 5 1
4 30320607 Co-operation of ABT-199 and gemcitabine in impeding DNA damage repair and inducing cell apoptosis for synergistic therapy of T-cell acute lymphoblastic leukemia. 2019 Feb 1
5 29138856 Differentially expressed proteins in the human esophageal cancer cell line Eca‑109, in the presence and absence of gemcitabine. 2018 Jan 1
6 26490978 Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer. 2016 Mar 1
7 25885284 Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101). 2015 Apr 7 1
8 21566062 Synergistic antitumor activity of gemcitabine and ABT-737 in vitro and in vivo through disrupting the interaction of USP9X and Mcl-1. 2011 Jul 3
9 18297287 Inducing apoptosis and enhancing chemosensitivity to gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell. 2008 Nov 2
10 18497956 Down-regulation of Mcl-1 with antisense technology alters the effect of various cytotoxic agents used in treatment of squamous cell carcinoma of the head and neck. 2008 Jun 1
11 16469407 Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes. 2006 Jun 1
12 12138244 Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes. 2002 3