7,8-dichloro-1,2,3,4-tetrahydroisoquinoline

phenylethanolamine-N-methyltransferase ; Rattus norvegicus







12 Article(s)
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1 8904737 Effect of phenylethanolamine N-methyltransferase inhibitor, CGS19281A, on the alpha-2-adrenoceptor function in the hypothalamus of rats in comparison with SKF29661, SKF64139 and yohimbine. 1996 1
2 8325998 Glucocorticoid induction of epinephrine synthesizing enzyme in rat skeletal muscle and insulin resistance. 1993 Jul 1
3 8458643 Glucocorticoid hypertension and nonadrenal phenylethanolamine N-methyltransferase. 1993 Apr 1
4 3342087 Possible mechanism of action of SKF 64139 in vivo on rat adrenal and brain phenylethanolamine N-methyltransferase activity. 1988 Jan 15 5
5 6489438 Acute cardiovascular effects of two central phenylethanolamine-N-methyl-transferase inhibitors in unanesthetized desoxycorticosterone-salt hypertensive rats. 1984 Jul 20 2
6 6358942 Effects of manipulating catecholamines on the incidence of the preovulatory surge of of luteinizing hormone and ovulation in the rat: evidence for a necessary involvement of hypothalamic adrenaline in the normal or 'midnight' surge. 1983 Sep 1
7 6132343 The influence of SK & F 64139, a phenylethanolamine-N-methyltransferase inhibitor, on centrally mediated cardiovascular effects of alpha-methyldopa and clonidine. 1982 Dec 1
8 6182406 Pre- and postsynaptic effects of SKF64139, a phenylethanolamine N-methyltransferase inhibitor, in conscious normotensive rats. 1982 Sep-Oct 3
9 7105433 Evidence that alpha-methylepinephrine is an antihypertensive metabolite of alpha-methyldopa. 1982 1
10 7227455 In vivo intraneuronal MAO inhibition in rat brain SKF 64139, comparison to other potent PNMT inhibitors. 1981 Mar 26 2
11 7293220 Metabolism of 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline, a phenylethanolamine N-methyltransferase inhibitor. I. Disposition following administration to the rat and dog. 1981 May 1
12 7293221 Metabolism of 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline, a phenylethanolamine N-methyltransferase inhibitor. II. Species difference in metabolism and synthesis of its metabolites. 1981 May 2