| 1 |
31655123 | Human CYP1A1 inhibition by flavonoids. | 2020 Feb |
3 |
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30680817 | Oroxylin A, a methylated metabolite of baicalein, exhibits a stronger inhibitory effect than baicalein on the CYP1B1-mediated carcinogenic estradiol metabolite formation. | 2019 Apr |
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| 3 |
31721711 | Ligand-Based Pharmacophore Modeling and Virtual Screening to Discover Novel CYP1A1 Inhibitors. | 2019 |
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| 4 |
29593542 | Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro. | 2018 |
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| 5 |
30448188 | Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells. | 2018 Dec 15 |
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28273931 | Dietary Flavonoids, CYP1A1 Genetic Variants, and the Risk of Colorectal Cancer in a Korean population. | 2017 Mar 9 |
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| 7 |
28632894 | Flavonoids as modulators of metabolic enzymes and drug transporters. | 2017 Jun |
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| 8 |
27551833 | Flavonoids and Naphthoflavonoids: Wider Roles in the Modulation of Cytochrome P450 Family 1 Enzymes. | 2016 Oct 6 |
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| 9 |
26757127 | Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation. | 2015 |
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23994263 | Benzo[a]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorin-5-methyl ether, via activation of cell signaling proteins and CYP1-mediated metabolism. | 2014 Oct 15 |
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25109996 | Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer. | 2014 Aug |
2 |
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22749133 | The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation. | 2013 Feb |
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22743247 | Bioactivation of the citrus flavonoid nobiletin by CYP1 enzymes in MCF7 breast adenocarcinoma cells. | 2012 Sep |
3 |
| 14 |
21329749 | Modulation of CYP1A1 activity by a Ginkgo biloba extract in the human intestinal Caco-2 cells. | 2011 May 10 |
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| 15 |
21482471 | Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids. | 2011 May 1 |
11 |
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21720915 | Interaction of a functionalized complex of the flavonoid hesperetin with the AhR pathway and CYP1A1 expression: involvement in its protective effects against benzo[a]pyrene-induced oxidative stress in human skin. | 2011 Oct |
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| 17 |
19608276 | Quercetin blocks caveolae-dependent pro-inflammatory responses induced by co-planar PCBs. | 2010 Nov |
2 |
| 18 |
20153368 | Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes. | 2010 Apr |
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20550209 | Metabolites of galangin by 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P450 1A1 in human intestinal epithelial Caco-2 cells and their antagonistic activity toward aryl hydrocarbon receptor. | 2010 Jul 14 |
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| 20 |
20696580 | Selective inhibition of methoxyflavonoids on human CYP1B1 activity. | 2010 Sep 1 |
5 |
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21053930 | Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives. | 2010 Dec 20 |
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| 22 |
18976853 | Bioactivation of the phytoestrogen diosmetin by CYP1 cytochromes P450. | 2009 Feb 8 |
2 |
| 23 |
19424633 | Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA-MB 468 breast cancer cells due to CYP1 activation. | 2009 Jun |
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| 24 |
19601638 | The methoxylated flavones eupatorin and cirsiliol induce CYP1 enzyme expression in MCF7 cells. | 2009 Aug |
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| 25 |
19666078 | CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells. | 2009 Oct 29 |
4 |
| 26 |
19766177 | CYP1A1 and CYP3A4 modulation by dietary flavonoids in human intestinal Caco-2 cells. | 2009 Dec 15 |
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| 27 |
17637178 | Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells. | 2007 Jun |
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| 28 |
16271822 | Inhibition of human cytochrome CYP 1 enzymes by flavonoids of St. John's wort. | 2006 Jan 16 |
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| 29 |
16454693 | Altered CYP expression and function in response to dietary factors: potential roles in disease pathogenesis. | 2006 Jan |
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| 30 |
16484233 | Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids. | 2006 Aug |
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| 31 |
17090139 | TCDD-induced CYP1A1 expression, an index of dioxin toxicity, is suppressed by flavonoids permeating the human intestinal Caco-2 cell monolayers. | 2006 Nov 15 |
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| 32 |
17159770 | Toxicological aspects of flavonoid interaction with biomacromolecules. | 2006 Dec |
5 |
| 33 |
16276964 | Effects of hydroxyl group numbers on the B-ring of 5,7-dihydroxyflavones on the differential inhibition of human CYP 1A and CYP1B1 enzymes. | 2005 Oct |
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| 34 |
12970578 | Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells. | 2003 Nov |
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| 35 |
11752233 | Flavonoids inhibit genetic toxicity produced by carcinogens in cells expressing CYP1A2 and CYP1A1. | 2002 Jan |
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| 36 |
11950788 | Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements. | 2002 May |
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| 37 |
11454723 | The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human cyp1a1 expression. | 2001 Aug |
4 |
| 38 |
10781868 | Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1. | 2000 Apr 3 |
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