Arsenic Trioxide

cytochrome c, somatic ; Homo sapiens







27 Article(s)
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1 33174611 Role of cofilin‑1 in arsenic trioxide‑induced apoptosis of NB4‑R1 cells. 2020 Dec 3
2 29314450 Ellagic acid mitigates arsenic-trioxide-induced mitochondrial dysfunction and cytotoxicity in SH-SY5Y cells. 2018 Feb 1
3 28966729 Arsenic Trioxide Induces Apoptosis via Specific Signaling Pathways in HT-29 Colon Cancer Cells. 2017 Jan 1
4 26607805 Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells. 2016 Feb 15 1
5 26987203 [Study on the resveratrol and arsenic trioxide combination induced apoptosis and its mechanism on lung adenocarcinoma cells]. 2016 Jan 1
6 25339131 Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression. 2015 Apr 1
7 25431299 Resveratrol synergistically triggers apoptotic cell death with arsenic trioxide via oxidative stress in human lung adenocarcinoma A549 cells. 2015 Feb 1
8 25932150 As2O3 induces apoptosis in human hepatocellular carcinoma HepG2 cells through a ROS-mediated mitochondrial pathway and activation of caspases. 2015 1
9 23041229 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways. 2012 Dec 15 1
10 20605902 Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines. 2010 Oct 1
11 21061466 Arsenic trioxide induces apoptosis in uveal melanoma cells through the mitochondrial pathway. 2010 1
12 18157160 Redox status of thioredoxin-1 (TRX1) determines the sensitivity of human liver carcinoma cells (HepG2) to arsenic trioxide-induced cell death. 2008 Apr 2
13 18158874 Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells. 2008 Jan 1
14 18359480 Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines. 2008 May 15 1
15 17203211 Arsenic trioxide induces apoptosis via the mitochondrial pathway by upregulating the expression of Bax and Bim in human B cells. 2007 Feb 1
16 17495969 Arsenic trioxide and proteasome inhibitor bortezomib synergistically induce apoptosis in leukemic cells: the role of protein kinase Cdelta. 2007 Jul 1
17 17673311 Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways. 2007 Nov 1
18 16685442 Combination treatment with arsenic trioxide and sulindac augments their apoptotic potential in lung cancer cells through activation of caspase cascade and mitochondrial dysfunction. 2006 Jun 1
19 16950207 Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin. 2006 Nov 15 1
20 15665116 Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells. 2005 May 15 1
21 15674346 Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway. 2005 Mar 10 1
22 16132712 mCICR is required for As2O3-induced permeability transition pore opening and cytochrome c release from mitochondria. 2005 Sep 1
23 14647451 Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide. 2004 Feb 12 1
24 12963972 Tetraarsenic oxide induces apoptosis in U937 leukemic cells through a reactive oxygen species-dependent pathway. 2003 Oct 1
25 14632209 Arsenic trioxide induces apoptosis of cutaneous T cell lymphoma cells: evidence for a partially caspase-independent pathway and potentiation by ascorbic acid (vitamin C). 2003 Oct 1
26 11172589 Potential role of caspase-3 and -9 in arsenic trioxide-mediated apoptosis in PCI-1 head and neck cancer cells. 2001 Feb 2
27 10477740 Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. 1999 Sep 15 1