Paclitaxel

cytochrome c, somatic ; Homo sapiens







36 Article(s)
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1 33848578 Synergistic effects of green tea extract and paclitaxel in the induction of mitochondrial apoptosis in ovarian cancer cell lines. 2021 Jun 30 1
2 30522045 Synergistic Activity of Paclitaxel, Sorafenib, and Radiation Therapy in advanced Renal Cell Carcinoma and Breast Cancer. 2019 Feb 1
3 29861445 Dual Acting Polymeric Nano-Aggregates for Liver Cancer Therapy. 2018 May 26 1
4 28350087 Paclitaxel induces apoptosis of esophageal squamous cell carcinoma cells by downregulating STAT3 phosphorylation at Ser727. 2017 Apr 1
5 28599444 Sulforaphane sensitizes human breast cancer cells to paclitaxel-induced apoptosis by downregulating the NF-κB signaling pathway. 2017 Jun 1
6 26985944 Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway. 2016 Mar 11 2
7 25339026 Sensitization of cervical carcinoma cells to paclitaxel by an IPP5 active mutant. 2014 1
8 23422592 The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer. 2013 May 1
9 23563171 Cytoprotective role of autophagy during paclitaxel-induced apoptosis in Saos-2 osteosarcoma cells. 2013 Jun 1
10 23698321 Confocal Raman data analysis enables identifying apoptosis of MCF-7 cells caused by anticancer drug paclitaxel. 2013 May 1
11 22221539 Novel water-soluble polyurethane nanomicelles for cancer chemotherapy: physicochemical characterization and cellular activities. 2012 Jan 5 1
12 19132448 Dynamic monitoring of apoptosis in chemotherapies with multiple fluorescence reporters. 2009 May-Jun 2
13 19331146 Critical role of bad phosphorylation by Akt in cytostatic resistance of human bladder cancer cells. 2009 Jan 2
14 19372481 Detection and quantification of the evolution dynamics of apoptosis using the PET voltage sensor 18F-fluorobenzyl triphenyl phosphonium. 2009 May 1
15 19459857 Vacuolar H+-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway. 2009 Aug 1
16 18452161 Involvement of endoplasmic reticulum in paclitaxel-induced apoptosis. 2008 Jul 1 1
17 17560963 Epothilone-paclitaxel resistant leukemic cells CEM/dEpoB300 are sensitive to albendazole: Involvement of apoptotic pathways. 2007 Aug 1 1
18 16051289 Enhancement of esculetin on Taxol-induced apoptosis in human hepatoma HepG2 cells. 2006 Jan 1 1
19 16528475 Regulation of survivin by retinoic acid and its role in paclitaxel-mediated cytotoxicity in MCF-7 breast cancer cells. 2006 Apr 1
20 15907983 Proteomic analysis of anti-cancer effects by paclitaxel treatment in cervical cancer cells. 2005 Jul 1
21 14726646 Arsenic trioxide and paclitaxel induce apoptosis by different mechanisms. 2004 Mar 1
22 15452117 Taxol induces caspase-10-dependent apoptosis. 2004 Dec 3 1
23 12700660 Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop. 2003 Apr 17 2
24 14680805 Antisense BAG-1 sensitizes HeLa cells to apoptosis by multiple pathways. 2003 Dec 19 1
25 14685027 Altered maturation of dendritic cells by taxol, an anticancer drug. 2003 Dec 1
26 12126962 Bcl-2 phosphorylation and proteasome-dependent degradation induced by paclitaxel treatment: consequences on sensitivity of isolated mitochondria to Bid. 2002 Aug 1 2
27 12459501 Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells. 2002 Dec 4 1
28 11408609 Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway. 2001 Jul 1
29 11600533 Cytochrome c release is upstream to activation of caspase-9, caspase-8, and caspase-3 in the enhanced apoptosis of anaplastic thyroid cancer cells induced by manumycin and paclitaxel. 2001 Oct 4
30 11707402 Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate. 2001 Nov 15 1
31 10699926 Late apoptotic effects of taxanes on K562 erythroleukemia cells: apoptosis is delayed upstream of caspase-3 activation. 2000 Feb 15 1
32 10769688 Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis. 2000 Jan-Feb 1
33 10822281 Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels. 2000 Jun 1
34 11034069 Paclitaxel induces release of cytochrome c from mitochondria isolated from human neuroblastoma cells'. 2000 Oct 1 2
35 9699642 "Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis. 1998 Aug 1 2
36 9844922 Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells. 1998 Dec 2