Tolbutamide

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







22 Article(s)
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1 32869328 An In Vitro and In Vivo Evaluation of the Effect of Relacorilant on the Activity of Cytochrome P450 Drug Metabolizing Enzymes. 2021 Feb 1
2 31744669 Validation of a sensitive UHPLC-MS/MS method for cytochrome P450 probe substrates caffeine, tolbutamide, dextromethorphan, and alprazolam in human serum reveals drug contamination of serum used for research. 2020 Feb 5 1
3 29989011 Inhibition of cytochrome P450 enzymes by thymoquinone in human liver microsomes. 2018 Jul 1
4 22765278 Effect of peginterferon alfa-2a (40KD) on cytochrome P450 isoenzyme activity. 2013 Feb 1
5 11742579 Interindividual variations in levels and activities of cytochrome P-450 in liver microsomes of Chinese subjects. 2001 Mar 1
6 10611138 Stimulation of tolbutamide hydroxylation by acetone and acetonitrile in human liver microsomes and in a cytochrome P-450 2C9-reconstituted system. 2000 Jan 1
7 10681382 CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes. 2000 Mar 2
8 9068933 A study of the potential effect of sertraline on the pharmacokinetics and protein binding of tolbutamide. 1997 2
9 8424795 Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily. 1993 Jan 15 2
10 1493081 Co-regulation of phenytoin and tolbutamide metabolism in humans. 1992 Dec 1
11 1857342 Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes. 1991 Jul 1
12 2049228 Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes. 1991 Feb 1
13 1974199 Tolbutamide hydroxylation by human, rabbit and rat liver microsomes and by purified forms of cytochrome P-450. 1990 May-Jun 2
14 2669966 Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae. 1989 Jun 13 1
15 3203057 In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulphonamides and quinolines. 1988 Jul 1
16 3355588 Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations. 1988 Mar 15 1
17 3383988 Selective inhibition of drug oxidation after simultaneous administration of two probe drugs, antipyrine and tolbutamide. 1988 1
18 3598900 Hepatic metabolism of tolbutamide: characterization of the form of cytochrome P-450 involved in methyl hydroxylation and relationship to in vivo disposition. 1987 Jun 2
19 3620298 Tolbutamide 4-hydroxylase activity of human liver microsomes: effect of inhibitors. 1987 Aug 1
20 3864428 Normal metabolism of debrisoquine and theophylline in a slow tolbutamide metaboliser. 1985 Jun 1
21 6860533 Evidence for a dual action of sulphinpyrazone on drug metabolism in man: theophylline-sulphinpyrazone interaction. 1983 May 1
22 913025 Mechanisms of inhibition of tolbutamide metabolism: phenylbutazone, oxyphenbutazone, sulfaphenazole. 1977 Nov 1