Warfarin

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







33 Article(s)
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1 32112562 The Magnitude of the Warfarin-Amiodarone Drug-Drug Interaction Varies With Renal Function: A Propensity-Matched Cohort Study. 2020 Jun 1
2 30689138 Should Cytochrome P450 Inducers be Used to Accelerate Clearance of Brodifacoum from Poisoned Patients? 2019 Mar 3
3 28118749 Warfarin Interaction With Hepatic Cytochrome P-450 Enzyme-Inducing Anticonvulsants. 2018 Jan 5
4 28686070 Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19. 2018 Jul 1
5 29858511 Cytochrome P450 genotype-guided drug therapies: An update on current states. 2018 Oct 2
6 26161443 A chiral HPLC-MS/MS method for simultaneous quantification of warfarin enantiomers and its major hydroxylation metabolites of CYP2C9 and CYP3A4 in human plasma. 2014 2
7 22317799 Warfarin genotyping in a single PCR reaction for microchip electrophoresis. 2012 Apr 1
8 18838506 Mechanism-based inactivation of cytochrome P450 2C9 by tienilic acid and (+/-)-suprofen: a comparison of kinetics and probe substrate selection. 2009 Jan 1
9 20002088 Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A. 2009 Dec 1
10 17708140 The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects. 2007 Aug 1 1
11 19356015 Prioritization of clinical drug interaction studies using in vitro cytochrome P450 data: proposed refinement and expansion of the "rank order" approach. 2007 Jan 1
12 16639745 Multiple molecular dynamics simulations of human p450 monooxygenase CYP2C9: the molecular basis of substrate binding and regioselectivity toward warfarin. 2006 Jul 1 4
13 15767245 Enhanced antithrombotic effect of warfarin associated with low-dose alcohol consumption. 2005 Feb 4
14 16162970 In-vitro cytotoxicity of ET-743 (Trabectedin, Yondelis), a marine anti-cancer drug, in the Hep G2 cell line: influence of cytochrome P450 and phase II inhibition, and cytochrome P450 induction. 2005 Oct 1
15 15197521 Increased liability of tramadol-warfarin interaction in individuals with mutations in the cytochrome P450 2D6 gene. 2004 Jul 1
16 12728288 Determination of bleeding risk using genetic markers in patients taking phenprocoumon. 2003 Jul 2
17 12814453 Evidence of an interaction between nifedipine and nafcillin in humans. 2003 Jun 2
18 11893129 The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. 2002 Mar 5
19 11343389 Extreme warfarin sensitivity in siblings associated with multiple cytochrome P450 polymorphisms. 2001 Jun 4
20 11523725 Pharmacogenetics of warfarin elimination and its clinical implications. 2001 2
21 10923005 Cytochrome P450 polymorphisms are associated with reduced warfarin dose. 2000 Aug 4
22 9068934 Effect of sertraline on protein binding of warfarin. 1997 2
23 8801056 Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies. 1996 Apr 2
24 8801058 Warfarin-fluconazole. III. A rational approach to management of a metabolically based drug interaction. 1996 Apr 1
25 1581537 Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions. 1992 Jan-Feb 3
26 3276317 Warfarin: metabolism and mode of action. 1988 Jan 1 2
27 2895455 Clinically important adverse effects and drug interactions with H2-receptor antagonists: an update. 1987 1
28 3333881 Aspects of anticoagulant action: a review of the pharmacology, metabolism and toxicology of warfarin and congeners. 1987 1
29 6096071 Interactions and non-interactions with ranitidine. 1984 Nov-Dec 1
30 6148215 Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin. 1984 Jul-Aug 4
31 6747992 The preferred solution conformation of warfarin at the active site of cytochrome P-450 based on the CD spectra in octanol/water model system. 1984 Aug 5
32 6860533 Evidence for a dual action of sulphinpyrazone on drug metabolism in man: theophylline-sulphinpyrazone interaction. 1983 May 2
33 31893 Cumene hydroperoxide-supported microsomal hydroxylations of warfarin--a probe of cytochrome P-450 multiplicity and specificity. 1979 1