Methylcholanthrene

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







31 Article(s)
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1 25336106 HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics. 2015 1
2 16867264 Influences of 3-methylcholanthrene, phenobarbital and dexamethasone on xenobiotic metabolizing-related cytochrome P450 enzymes and steroidogenesis in human fetal adrenal cortical cells. 2006 Aug 2
3 11967242 Methoxyestradiols mediate estradiol-induced antimitogenesis in human aortic SMCs. 2002 Apr 2
4 11497333 Metabolism of aflatoxin B1 by normal human bronchial epithelial cells. 2001 Aug 10 4
5 9454825 Human hepatocyte growth factor down-regulates the expression of cytochrome P450 isozymes in human hepatocytes in primary culture. 1998 Feb 1
6 1768430 Induction and inhibition of NAD(P)H: quinone reductase in murine and human skin. 1991 1
7 1771946 [Assessment of biotransformation capacity following oral administration of various model substances as cocktail]. 1991 Dec 1
8 1914510 Immunocytochemical study of phenobarbital- and 3-methylcholanthrene-inducible cytochrome P450 isozymes in primary cultures of porcine ciliary epithelium. 1991 Aug 1
9 2219115 Acetaminophen structure-toxicity studies: in vivo covalent binding of a nonhepatotoxic analog, 3-hydroxyacetanilide. 1990 Sep 1 1
10 2220168 [Effect of a new gestagen--dienogest--and its combination with ethinyl estradiol on the activity of biotransformation reactions]. 1990 1
11 2398265 Drug metabolism in end-stage liver disease. In vitro activities of some phase I and phase II enzymes. 1990 Jul 1
12 20837414 The induction by monochlorodibenzofuran isomers of xenobiotic metabolizing systems in cell lines derived from rat and human hepatoma. 1990 1
13 2512389 Comparison of the formation of benzo[a]pyrene diolepoxide-DNA adducts in vitro by rat and human microsomes: evidence for the involvement of P-450IA1 and P-450IA2. 1989 Summer 1
14 2703963 Biliary excretion of acetaminophen-glutathione as an index of toxic activation of acetaminophen: effect of chemicals that alter acetaminophen hepatotoxicity. 1989 Mar 1
15 3304211 The role of conjugation reactions in detoxication. 1987 1
16 3445541 [Effect of different inactivating agents on microsomal cytochromes P-450 and P-448]. 1987 Nov-Dec 1
17 2425856 [Induction of the phenobarbital form of cytochrome P-450 by chemically unrelated compounds]. 1986 Jul 2
18 3517618 Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat. 1986 Apr 1
19 3873598 Monoclonal antibody-directed determination of cytochrome P-450 types expressed in a human lymphoblastoid cell line. 1985 Jun 1
20 3965304 Catalytic activity of the membrane-bound methylcholanthrene-inducible cytochrome P-450. 1985 Jan 1 2
21 3986002 Altered induction response of hepatic cytochrome P-450 to phenobarbital, 3-methylcholanthrene, and beta-naphthoflavone in organotin-treated animals. 1985 Apr 1 2
22 3991787 [Determination of caffeine and metamizole elimination in men and women with and without hormonal contraceptives as an in vivo method for characterization of various cytochrome P-450 subspecies]. 1985 Jan 1
23 4095131 [Elimination of caffeine and metamizol in in vivo characterization of cytochrome P-450 dependent biotransformation reactions in aged humans]. 1985 Nov 1
24 4095132 [The influence of chronic renal insufficiency on the demethylating activities of various cytochrome P-450 subspecies in humans]. 1985 Nov 1
25 6438379 Cytochrome P-450-dependent oxidative cleavage of 1-(tetrahydro-2-furanyl)-5-fluorouracil to 5-fluorouracil. 1984 Sep 1
26 6411467 Characterisation of hepatocyte sub-populations generated by centrifugal elutriation. 1983 Aug 15 1
27 6980417 Phenotyping of cytochromes P-450 in human tissues with monoclonal antibodies. 1982 Jun 1
28 7054190 Effects of 3-methylcholanthrene, beta-naphthoflavone, and phenobarbital on the 3-methylcholanthrene-inducible isozyme of cytochrome P-450 within centrilobular, midzonal, and periportal hepatocytes. 1982 Jan 25 2
29 719999 The nature of hepatic cytochrone P-450 induced in hexachlorobenzene-fed rats. 1978 Nov 2
30 948753 Cytochrome P-450 induction by phenobarbital and 3-methylcholanthrene in primary cultures of hepatocytes. 1976 Sep 3 1
31 5688265 Effect of partial hepatectomy of the responsiveness of microsomal enzymes and cytochrome P-450 to phenobarbital or 3-methylcholanthrene. 1968 Sep 1