Metyrapone

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







34 Article(s)
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1 16162970 In-vitro cytotoxicity of ET-743 (Trabectedin, Yondelis), a marine anti-cancer drug, in the Hep G2 cell line: influence of cytochrome P450 and phase II inhibition, and cytochrome P450 induction. 2005 Oct 1
2 11869873 Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. 2002 Apr 1
3 10611146 Effect of the adrenal 11-beta-hydroxylase inhibitor metyrapone on human hepatic cytochrome P-450 expression: induction of cytochrome P-450 3A4. 2000 Jan 1
4 8171446 In vitro bioactivation of the environmental pollutant 3-methylsulphonyl-2, 2-bis(4-chlorophenyl)-1,1-dichloroethene in the human adrenal gland. 1994 Apr 1
5 1967940 Metyrapone modulation of tyrosine aminotransferase induction by dexamethasone in cultured hepatocytes. 1990 Jan 30 2
6 2238705 Studies on the cytochrome P-450 of avocado (Persea [corrected] americana) mesocarp microsomal fraction. 1990 Jul 1
7 2242730 [The effect of monensin, tiamulin and the simultaneous administration of both substances on the microsomal mixed function oxidases and on the peroxide formation in broilers]. 1990 Sep 1
8 2559440 Oxidation of diethyldithiocarbamate to disulfiram by liver microsomal cytochrome P-450-containing monooxygenase system. 1989 Oct 1
9 3132330 The oxidation of tetrachloro-1,4-hydroquinone by microsomes and purified cytochrome P-450b. Implications for covalent binding to protein and involvement of reactive oxygen species. 1988 1
10 3419164 The reoxidation of cytochrome P-450 by paraquat inhibits aldosterone biosynthesis from 18-hydroxycorticosterone. 1988 Sep 1
11 3027305 Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells. 1987 Jan 1
12 3111319 Lipid mediators in the control of the ductus arteriosus. 1987 Jul 1
13 2425812 Induction of sister chromatid exchanges in human and rat hepatoma cell lines by cyclophosphamide and phosphoramide mustard and the effects of cytochrome P-450 inhibitors. 1986 Jul 1 1
14 3983470 Effect of the antioxidant (+)-cyanidanol-3 on H2O2 formation and lipid peroxidation in liver microsomes. 1985 Jan 1
15 6200138 Enhancement of bleomycin-mediated DNA damage by epidermal microsomal enzymes. 1984 Apr 5 1
16 6661247 Hepatic microsomal cytochrome p-450-dependent N-demethylation of methylguanidine. 1983 Dec 15 3
17 6279597 Low temperature EPR spectroscopic characterization of the interaction of cytochrome P-450cam with a spin label analog of metyrapone. 1982 May 25 1
18 6292686 Microsomal reduction of gentian violet. Evidence for cytochrome P-450-catalyzed free radical formation. 1982 Sep 1
19 7103956 Limitations on the metyrapone assay for the major phenobarbital inducible form of cytochrome P-450. 1982 Apr 29 1
20 6457649 Comparison of the effects of inhibitors of cytochrome P-450-mediated reactions on human platelet aggregation and arachidonic acid metabolism. 1981 Oct 12 2
21 7285278 Chloroethanes : their metabolism by hepatic cytochrome P-450 in vitro. 1981 1
22 7297566 Cytochrome P-450 monooxygenase activities in human and rat liver microsomes. 1981 Sep 1 1
23 21043244 Biphasic O-deethylation of phenacetin and 7-ethoxycoumarin by human and rat liver microsomal fractions. 1981 Sep 1 1
24 6779432 [Cytochrome P-450 dependent enzymatic activity in the liver of patients with porphyria cutanea tarda (author's transl)]. 1980 Oct 1
25 428008 Fate of juvenile hormone in mammalian cell culture. 1979 Feb 1
26 182488 Binding of a metyrapone spin label to microsomal cytochrome P-450. 1976 Jun 15 6
27 954149 A new class of inhibitory cytochrome P-450 complexes formed during metabolism: a comparison with amphetamine and SKF 525-A type complexes. 1976 Aug 1
28 1262443 Dual sites of inhibition by metyrapone of human adrenal steroidogenesis: correlation of in vivo and in vitro studies. 1976 Apr 1
29 240656 Interaction of aromatic nitro compounds with reduced hepatic microsomal cytochrome P-450. 1975 Jul-Aug 2
30 4267597 Active centers of microsomal cytochrome P-450 determined with metyrapone by mutural depletion system kinetics. 1973 1
31 4570969 The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions. 1972 1
32 5144763 The binding of metyrapone to cytochrome P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions. 1971 Nov 1
33 5433592 In vivo interaction of metyrapone with adrenal cortical mitochondrial cytochrome P-450. 1970 Jun 1
34 5805284 The interaction of metopirone with adrenal mitochondrial cytochrome P-450. A mechanism for the inhibition of adrenal steroid 11 beta-hydroxylation. 1969 Apr 1