Polycyclic Aromatic Hydrocarbons

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







39 Article(s)
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1 32094037 Smoking cessation and duloxetine toxicity: A case report. 2020 Jul - Aug 2
2 30576387 Polycyclic aromatic hydrocarbons (PAHs) present in ambient urban dust drive proinflammatory T cell and dendritic cell responses via the aryl hydrocarbon receptor (AHR) in vitro. 2018 3
3 25398514 Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism. 2016 Feb 4
4 26247835 Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13. 2016 1
5 27251443 Transcription of a novel P450 gene varies with some factors (pollutant exposure, temperature, time, and body region) in a marine oligochaete (Thalassodrilides sp.). 2016 Aug 15 4
6 26082767 Polycyclic aromatic hydrocarbons and cytochrome P450 in HIV pathogenesis. 2015 3
7 23432465 Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6. 2013 Apr 15 2
8 20051482 Persistent induction of cytochrome P4501A1 in human hepatoma cells by 3-methylcholanthrene: evidence for sustained transcriptional activation of the CYP1A1 promoter. 2010 Apr 2
9 19330882 Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1. 2009 May 15 4
10 17292855 Evaluation of cytochrome P450(BSbeta) reactivity against polycyclic aromatic hydrocarbons and drugs. 2007 Mar 30 3
11 17413125 The growing burden of chronic obstructive pulmonary disease and lung cancer in women: examining sex differences in cigarette smoke metabolism. 2007 Jul 15 2
12 17823102 Drug interactions with smoking. 2007 Sep 15 2
13 15836631 Constitutive expression and localization of cytochrome P-450 1A1 in rat and human brain: presence of a splice variant form in human brain. 2005 May 1
14 16202979 CYP1A1-mediated mechanism for atherosclerosis induced by polycyclic aromatic hydrocarbons. 2005 Nov 18 4
15 15081398 Cytochrome P450-dependent toxicity of environmental polycyclic aromatic hydrocarbons towards human macrophages. 2004 May 7 1
16 15315710 Inducible cytochrome P450 activities in renal glomerular mesangial cells: biochemical basis for antagonistic interactions among nephrocarcinogenic polycyclic aromatic hydrocarbons. 2004 Aug 17 1
17 12490585 Blockage of multidrug resistance-associated proteins potentiates the inhibitory effects of arsenic trioxide on CYP1A1 induction by polycyclic aromatic hydrocarbons. 2003 Jan 1
18 12930004 Paraxanthine/caffeine ratio: as an index for CYP1A2 activity in polycyclic aromatic hydrocarbons exposed subjects. 2003 Jun 2
19 14582238 [Molecular epidemiology in occupational medicine: methodological features and impact of individual genetic susceptibility]. 2003 Jul-Sep 2
20 11311457 Changes in the expression of cytochrome P450 2E1 and the activity of carcinogen-metabolizing enzymes in Schistosoma haematobium-infected human bladder tissues. 2001 Apr 12 2
21 11497333 Metabolism of aflatoxin B1 by normal human bronchial epithelial cells. 2001 Aug 10 2
22 11506821 Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens. 2001 Sep 1 1
23 11524025 Smoking in patients receiving psychotropic medications: a pharmacokinetic perspective. 2001 2
24 10797280 Expression of CYP1A1, CYP1B1 and CYP3A, and polycyclic aromatic hydrocarbon-DNA adduct formation in bronchoalveolar macrophages of smokers and non-smokers. 2000 Jun 1 6
25 9442307 Risk assessment for complex chemical exposure in aquatic systems: the problem of estimating interactive effects. 1998 1
26 7901425 Relationship between genotype and function of the human CYP1A1 gene. 1993 Oct-Nov 1
27 1336724 Immunohistochemical detection of pulmonary cytochrome P450IA and metabolic activities associated with P450IA1 and P450IA2 isozymes in lung cancer patients. 1992 Nov 1
28 1344831 [Omeprazole and liver functions]. 1992 Sep-Oct 1
29 2509067 Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. 1989 Nov 15 1
30 2882985 Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes. 1987 Mar-Apr 1
31 3593412 Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies. 1987 Apr 15 1
32 3608349 A urinary metabolite ratio that reflects systemic caffeine clearance. 1987 Aug 1
33 3689370 7-Ethoxyresorufin-O-deethylase activity in human hair roots: a potential marker for toxifying species of cytochrome P-450 isozymes. 1987 Oct 29 4
34 3689794 Anthraflavic acid is a potent and specific inhibitor of cytochrome P-448 activity. 1987 Dec 18 1
35 3004505 Xenobiotic-metabolizing enzyme activity in human non-small-cell derived lung cancer cell lines. 1986 Feb 15 1
36 3790107 The molecular biology of the polycyclic aromatic hydrocarbon inducible cytochrome P-450; the past is prologue. 1986 Jan 1
37 3839750 Identification and quantification of a messenger ribonucleic acid induced by polynuclear aromatic hydrocarbons--using a cloned human cytochrome P-450 gene. 1985 Sep 16 1
38 7344478 Regio- and stereoselectivity of hepatic cytochrome P-450 toward polycyclic aromatic hydrocarbon substrates. 1981 2
39 6105054 Correlations between cytochrome P-450 and oxidative metabolism of benzo[a]pyrene and 7-ethoxycoumarin in human liver in vitro and antipyrine elimination in vivo. 1980 Jul-Aug 1