benzyloxycarbonylleucyl-leucyl-leucine aldehyde

CASP8 and FADD like apoptosis regulator ; Homo sapiens







15 Article(s)
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1 26415225 The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition. 2015 Oct 27 1
2 23519470 Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein. 2013 May 3 2
3 23559011 Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells. 2013 Apr 4 1
4 22345097 The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition. 2012 Apr 1
5 22923157 Autophagy modulators sensitize prostate epithelial cancer cell lines to TNF-alpha-dependent apoptosis. 2012 Nov 2
6 23256568 Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cells. 2012 Dec 21 2
7 21170508 Berberine sensitizes TRAIL-induced apoptosis through proteasome-mediated downregulation of c-FLIP and Mcl-1 proteins. 2011 Feb 2
8 21206980 Proteasome inhibitor sensitizes oral squamous cell carcinoma cells to TRAIL-mediated apoptosis. 2011 Mar 2
9 21283566 β-Elemene piperazine derivatives induce apoptosis in human leukemia cells through downregulation of c-FLIP and generation of ROS. 2011 Jan 25 1
10 21868755 Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3. 2011 Oct 1 2
11 20442774 c-FLIP degradation mediates sensitization of pancreatic cancer cells to TRAIL-induced apoptosis by the histone deacetylase inhibitor LBH589. 2010 Apr 28 1
12 18645030 The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 Jul 1
13 19001438 Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells. 2008 Nov 1
14 17332355 MG-132 sensitizes TRAIL-resistant prostate cancer cells by activating c-Fos/c-Jun heterodimers and repressing c-FLIP(L). 2007 Mar 1 5
15 16082182 Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation. 2005 Jul 1