| 1 |
35606478 | Lack of association of CYP2B6 pharmacogenetics with cyclophosphamide toxicity in patients with cancer. | 2022 May 24 |
1 |
| 2 |
35618489 | 3D-QSAR and scaffold hopping based designing of benzo[d]ox-azol-2(3H)-one and 2-oxazolo[4,5-b]pyridin-2(3H)-one derivatives as selective aldehyde dehydrogenase 1A1 inhibitors: Synthesis and biological evaluation. | 2022 May 26 |
1 |
| 3 |
34057116 | Increased aldehyde dehydrogenase 1 (ALDH1) levels are associated with chemo-responsiveness in breast cancer patients treated with taxane-adriamycin-cyclophosphamide regimen. | 2021 |
3 |
| 4 |
34089986 | Multiple machine learning models combined with virtual screening and molecular docking to identify selective human ALDH1A1 inhibitors. | 2021 Sep |
1 |
| 5 |
32877739 | Investigating the Role of Missense SNPs on ALDH 1A1 mediated pharmacokinetic resistance to cyclophosphamide. | 2020 Oct |
1 |
| 6 |
26398662 | Combined expression of aldehyde dehydrogenase 1A1 and β-catenin is associated with lymph node metastasis and poor survival in breast cancer patients following cyclophosphamide treatment. | 2015 Dec |
3 |
| 7 |
24387105 | Selective ALDH3A1 inhibition by benzimidazole analogues increase mafosfamide sensitivity in cancer cells. | 2014 Jan 23 |
2 |
| 8 |
25344211 | ALDH1A1 mediates resistance of diffuse large B cell lymphoma to the CHOP regimen. | 2014 Dec |
1 |
| 9 |
22080062 | Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity, and outcome to neoadjuvant chemotherapy. | 2012 Mar |
2 |
| 10 |
18496131 | Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide. | 2008 Jun |
1 |
| 11 |
18560594 | Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. | 2008 Jun 18 |
1 |
| 12 |
16614850 | RNAi-mediated knockdown of aldehyde dehydrogenase class-1A1 and class-3A1 is specific and reveals that each contributes equally to the resistance against 4-hydroperoxycyclophosphamide. | 2007 Jan |
2 |
| 13 |
11914911 | Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: a retrospective study. Rational individualization of oxazaphosphorine-based cancer chemotherapeutic regimens. | 2002 Apr |
7 |
| 14 |
12513786 | Aldehyde-dehydrogenase gene-transduced hematopoietic cell line K562 overcomes the cytoxicity of cyclophosphamide in vitro. | 2002 Jun |
4 |
| 15 |
11320670 | Primary breast tumor levels of suspected molecular determinants of cellular sensitivity to cyclophosphamide, ifosfamide, and certain other anticancer agents as predictors of paired metastatic tumor levels of these determinants. Rational individualization of cancer chemotherapeutic regimens. | 2001 Mar |
1 |
| 16 |
10773007 | Expression of antisense RNA to aldehyde dehydrogenase class-1 sensitizes tumor cells to 4-hydroperoxycyclophosphamide in vitro. | 2000 May |
2 |
| 17 |
9884322 | Inhibition of human aldehyde dehydrogenase 1 by the 4-hydroxycyclophosphamide degradation product acrolein. | 1999 Jan |
3 |
| 18 |
10469894 | Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines. | 1999 Aug |
1 |
| 19 |
11741210 | Inhibition of carboxyethylphosphoramide mustard formation from 4-hydroxycyclophosphamide by carmustine. | 1999 |
1 |
| 20 |
9551609 | In vitro selection for K562 cells with higher retrovirally mediated copy number of aldehyde dehydrogenase class-1 and higher resistance to 4-hydroperoxycyclophosphamide. | 1998 Mar 20 |
2 |
| 21 |
9322086 | Coding region-specific destabilization of mRNA transcripts attenuates expression from retroviral vectors containing class 1 aldehyde dehydrogenase cDNAs. | 1997 Sep 1 |
2 |
| 22 |
9394035 | Relative contribution of human erythrocyte aldehyde dehydrogenase to the systemic detoxification of the oxazaphosphorines. | 1997 Dec |
1 |
| 23 |
9815579 | Cellular levels of class 1 and class 3 aldehyde dehydrogenases and certain other drug-metabolizing enzymes in human breast malignancies. | 1997 Nov |
1 |
| 24 |
8562935 | Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer. | 1996 Feb 1 |
3 |
| 25 |
8662658 | De novo expression of transfected human class 1 aldehyde dehydrogenase (ALDH) causes resistance to oxazaphosphorine anti-cancer alkylating agents in hamster V79 cell lines. Elevated class 1 ALDH activity is closely correlated with reduction in DNA interstrand cross-linking and lethality. | 1996 May 17 |
1 |
| 26 |
8785707 | Overexpression of the human aldehyde dehydrogenase class I results in increased resistance to 4-hydroperoxycyclophosphamide. | 1996 Jan-Feb |
2 |