Acetylcysteine

interleukin 1 beta ; Homo sapiens







47 Article(s)
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1 30847537 Carbon nanotubes and crystalline silica stimulate robust ROS production, inflammasome activation, and IL-1β secretion in macrophages to induce myofibroblast transformation. 2019 Apr 1
2 31521245 Melatonin alleviates cigarette smoke-induced endothelial cell pyroptosis through inhibiting ROS/NLRP3 axis. 2019 Nov 5 2
3 31577702 N-acetyl cysteine inhibits lipopolysaccharide-mediated synthesis of interleukin-1β and tumor necrosis factor-α in human periodontal ligament fibroblast cells through nuclear factor-kappa B signaling. 2019 Oct 3
4 28118826 Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation. 2017 Jan 24 1
5 28335600 Redox Potential-Sensitive N-Acetyl Cysteine-Prodrug Nanoparticles Inhibit the Activation of Microglia and Improve Neuronal Survival. 2017 May 1 1
6 26659566 Indoxyl sulfate enhances IL-1β-induced E-selectin expression in endothelial cells in acute kidney injury by the ROS/MAPKs/NFκB/AP-1 pathway. 2016 Nov 1
7 26908203 Induction of IL-8(CXCL8) and MCP-1(CCL2) with oxidative stress and its inhibition with N-acetyl cysteine (NAC) in cell culture model using HK-2 cell. 2016 Mar 2
8 25327779 Activation of NLRP3 and AIM2 inflammasomes in Kupffer cells in hepatic ischemia/reperfusion. 2015 Jan 1
9 25575547 The anti-inflammatory effects of acetaminophen and N-acetylcysteine through suppression of the NLRP3 inflammasome pathway in LPS-challenged piglet mononuclear phagocytes. 2015 Aug 1
10 25666878 N-acetyl cysteine reduces oxidative toxicity, apoptosis, and calcium entry through TRPV1 channels in the neutrophils of patients with polycystic ovary syndrome. 2015 Mar 1
11 25701684 Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients. 2015 May 1
12 25834143 Helicobacter pylori induces IL-1β and IL-18 production in human monocytic cell line through activation of NLRP3 inflammasome via ROS signaling pathway. 2015 Jun 1
13 25863775 Mechanisms that lead to the regulation of NLRP3 inflammasome expression and activation in human dental pulp fibroblasts. 2015 Aug 1
14 25971793 Sesquiterpene lactone parthenolide attenuates production of inflammatory mediators by suppressing the Toll-like receptor-4-mediated activation of the Akt, mTOR, and NF-κB pathways. 2015 Sep 1
15 26335060 Involvement of nitric oxide in the induction of interleukin-1 beta in microglia. 2015 Nov 2 1
16 25218171 Reactive oxygen species mediate IL-8 expression in Down syndrome candidate region-1-overexpressed cells. 2014 Oct 1
17 23434081 The combination effects of acetaminophen and N-acetylcysteine on cytokines production and NF-κB activation of lipopolysaccharide-challenged piglet mononuclear phagocytes in vitro and in vivo. 2013 Apr 15 1
18 23687429 The protective effect of antioxidants on orbital fibroblasts from patients with Graves' ophthalmopathy in response to oxidative stress. 2013 1
19 23874646 Particle size of latex beads dictates IL-1β production mechanism. 2013 3
20 22867088 Glutathione-S-transferase M1 regulation of diesel exhaust particle-induced pro-inflammatory mediator expression in normal human bronchial epithelial cells. 2012 Aug 6 1
21 21424515 Anti-inflammatory properties of N-acetylcysteine on lipopolysaccharide-activated macrophages. 2011 Jul 1
22 22092168 Effect of N-acetylcysteine on cardiac injury and oxidative stress after abdominal aortic aneurysm repair: a randomized controlled trial. 2011 Sep 1
23 22111911 Amino-functionalized polystyrene nanoparticles activate the NLRP3 inflammasome in human macrophages. 2011 Dec 27 1
24 19379726 Pyrrolidine dithiocarbamate, a NF-kappaB inhibitor, upregulates MMP-1 and MMP-13 in IL-1beta-stimulated rheumatoid arthritis fibroblast-like synoviocytes. 2009 Jun 24 1
25 19765584 Differential effects of the antioxidant n-acetylcysteine on the production of catabolic mediators in IL-1beta-stimulated human osteoarthritic synoviocytes and chondrocytes. 2009 Nov 25 3
26 20560295 N-acetylcysteine inhibits TNF-alpha, sTNFR, and TGF-beta1 release by alveolar macrophages in idiopathic pulmonary fibrosis in vitro. 2009 Jul 1
27 17135302 ROS and NF-kappaB but not LXR mediate IL-1beta signaling for the downregulation of ATP-binding cassette transporter A1. 2007 Apr 1
28 17765224 Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells. 2007 Oct 2
29 17072061 Influence of N-acetylcysteine on ICAM-1 expression and IL-8 release from endothelial and epithelial cells. 2006 Sep 4
30 15733769 N-Acetylcysteine administered as part of the immediate post-traumatic resuscitation regimen does not significantly influence initiation of inflammatory responses or subsequent endotoxin hyporesponsiveness. 2005 Mar 1
31 16109311 Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes. 2005 Sep 15 2
32 15208668 Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells. 2004 Aug 26 2
33 15470276 HAART drugs induce oxidative stress in human endothelial cells and increase endothelial recruitment of mononuclear cells: exacerbation by inflammatory cytokines and amelioration by antioxidants. 2004 1
34 12882449 N-acetylcysteine reduces chemokine release via inhibition of p38 MAPK in human airway smooth muscle cells. 2003 Jul 7
35 14690293 Comparison of different anti-inflammatory agents in suppressing the monocyte response to orthopedic particles. 2003 Dec 1
36 12079021 Inhibition of polymethylmethacrylate particle-induced monocyte activation and IL-1beta and TNF-alpha expression by the antioxidant agent N-acetylcysteine. 2002 Apr 2
37 11709424 Role of reactive oxygen species in IL-1 beta-stimulated sustained ERK activation and MMP-9 induction. 2001 Dec 3
38 10925209 Synergistic anticancer activity of 1,25-dihydroxyvitamin D(3) and immune cytokines: the involvement of reactive oxygen species. 2000 Jun 1
39 11032359 U373-MG response to interleukin-1beta-induced oxidative stress. 2000 1
40 11079466 Regulation of cyclooxygenase-2 expression in human osteoblastic cells by N-acetylcysteine. 2000 Nov 5
41 10063910 Redox regulation of interleukin-8 expression in MKN28 cells. 1999 Feb 4
42 9581775 NF-kappaB protects HIV-1-infected myeloid cells from apoptosis. 1998 Apr 25 2
43 9099744 Interleukin-1beta induction of mitogen-activated protein kinases in human mesangial cells. Role of oxidation. 1997 Apr 18 1
44 8639020 N-acetylcysteine inhibits production of tumor necrosis factor alpha and interleukin-1 beta. 1996 Jun 10 1
45 8669050 [Radiation protection through cytokine release by N-acetylcysteine]. 1996 Feb 1
46 7545088 Effects of anti-nuclear factor kappa B reagents in blocking adhesion of human cancer cells to vascular endothelial cells. 1995 Sep 15 1
47 7691889 Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. 1993 Oct 4