| 1 |
35324017 | Conformations and binding pockets of HRas and its guanine nucleotide exchange factors complexes in the guanosine triphosphate exchange process. | 2022 May 15 |
1 |
| 2 |
28139825 | Attenuated phenotype of Costello syndrome and early death in a patient with an HRAS mutation (c.179G>T; p.Gly60Val) affecting signalling dynamics. | 2017 Sep |
1 |
| 3 |
25946318 | Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells. | 2015 Jun |
1 |
| 4 |
23335589 | Functional analysis of a duplication (p.E63_D69dup) in the switch II region of HRAS: new aspects of the molecular pathogenesis underlying Costello syndrome. | 2013 Apr 15 |
1 |
| 5 |
20018863 | Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics. | 2010 Feb 19 |
1 |
| 6 |
18790720 | Binding of calcium ions to Ras promotes Ras guanine nucleotide exchange under emulated physiological conditions. | 2008 Nov |
4 |
| 7 |
16415107 | S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells. | 2006 Mar |
1 |
| 8 |
16841939 | Detailed map of oxidative post-translational modifications of human p21ras using Fourier transform mass spectrometry. | 2006 Jul 15 |
1 |
| 9 |
14749369 | Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors. | 2004 Feb |
1 |
| 10 |
14979728 | Mechanism of p21Ras S-nitrosylation and kinetics of nitric oxide-mediated guanine nucleotide exchange. | 2004 Mar 2 |
1 |
| 11 |
11948427 | SmgGDS displays differential binding and exchange activity towards different Ras isoforms. | 2002 Apr 4 |
1 |
| 12 |
11075717 | The functional significance of Shc in insulin signaling as a substrate of the insulin receptor. | 2000 Aug |
1 |
| 13 |
10049745 | VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases. | 1999 Feb 16 |
1 |
| 14 |
10498616 | M-Ras, a widely expressed 29-kD homologue of p21 Ras: expression of a constitutively active mutant results in factor-independent growth of an interleukin-3-dependent cell line. | 1999 Oct 1 |
1 |
| 15 |
9722985 | Mutation of aspartate-233 to valine in mouse ornithine decarboxylase reduces enzyme activity. | 1998 Jul |
1 |
| 16 |
9434775 | Perillic acid inhibits Ras/MAP kinase-driven IL-2 production in human T lymphocytes. | 1997 Dec 29 |
1 |
| 17 |
8636102 | Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor. | 1996 Mar 22 |
1 |
| 18 |
8950985 | Rasp21 sequences opposite the nucleotide binding pocket are required for GRF-mediated nucleotide release. | 1996 Nov 21 |
1 |
| 19 |
9115849 | Recombinant human alpha 2-HS glycoprotein inhibits insulin-stimulated mitogenic pathway without affecting metabolic signalling in Chinese hamster ovary cells overexpressing the human insulin receptor. | 1996 Dec |
1 |
| 20 |
7487952 | The novel cyclic dinucleotide 3'-5' cyclic diguanylic acid binds to p21ras and enhances DNA synthesis but not cell replication in the Molt 4 cell line. | 1995 Nov 1 |
1 |
| 21 |
7608150 | Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless. | 1995 Jul 7 |
1 |
| 22 |
7673152 | p21ras as a common signaling target of reactive free radicals and cellular redox stress. | 1995 Sep 8 |
1 |
| 23 |
7706235 | Nitric oxide-stimulated guanine nucleotide exchange on p21ras. | 1995 Mar 31 |
2 |
| 24 |
7718090 | The regulation and function of p21ras during T-cell activation and growth. | 1995 Mar |
1 |
| 25 |
8524141 | Analysis of intrinsic and CDC25-stimulated guanine nucleotide exchange of p21ras-nucleotide complexes by fluorescence measurements. | 1995 |
1 |
| 26 |
7809086 | Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap. | 1994 Dec 20 |
1 |
| 27 |
7917105 | G proteins in lymphocyte signalling. | 1994 Jun |
1 |
| 28 |
7972015 | Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. | 1994 Nov 8 |
2 |
| 29 |
7988425 | Insulin and epidermal growth factor influence guanine nucleotide-releasing factor by distinct mechanisms. | 1994 Dec |
1 |
| 30 |
8142894 | Hydrogen bond interactions of G proteins with the guanine ring moiety of guanine nucleotides. | 1994 Jan |
1 |
| 31 |
8196614 | Two types of RAS mutants that dominantly interfere with activators of RAS. | 1994 Jun |
1 |
| 32 |
8260648 | Regulation of PtdIns-3-kinase and the guanine nucleotide binding proteins p21ras during signal transduction by the T cell antigen receptor and the interleukin-2 receptor. | 1993 Oct |
1 |
| 33 |
8299426 | Three-dimensional structure and properties of wild-type and mutant H-ras-encoded p21. | 1993 |
1 |
| 34 |
8361768 | Identification of amino acids in p21ras involved in exchange factor interaction. | 1993 Sep |
1 |
| 35 |
8386636 | Nucleotide binding and GTP hydrolysis by the 21-kDa product of the c-H-ras gene as monitored by proton-NMR spectroscopy. | 1993 Apr 15 |
1 |
| 36 |
8417322 | Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras. | 1993 Jan |
2 |
| 37 |
8496156 | Interaction of GTPase activating proteins (GAPs) with p21ras measured by a novel fluorescence anisotropy method. Essential role of Arg-903 of GAP in activation of GTP hydrolysis on p21ras. | 1993 May 25 |
1 |
| 38 |
1395932 | T lymphocyte activation signals. | 1992 |
2 |
| 39 |
1532814 | The growth factor IL-2 activates p21ras proteins in normal human T lymphocytes. | 1992 Apr 15 |
1 |
| 40 |
1633420 | Regulation of p21ras by GTPase activating proteins and guanine nucleotide exchange proteins. | 1992 Feb |
1 |
| 41 |
1741165 | Isolation of azatyrosine-induced revertants from ras-transformed human mammary epithelial cells. | 1992 Jan |
1 |
| 42 |
1674518 | CD2 antigen mediated activation of the guanine nucleotide binding proteins p21ras in human T lymphocytes. | 1991 Jun 1 |
2 |
| 43 |
1785141 | The structure of Ras protein: a model for a universal molecular switch. | 1991 Oct |
2 |
| 44 |
1903516 | Bcr encodes a GTPase-activating protein for p21rac. | 1991 May 30 |
1 |
| 45 |
2038322 | A ras effector domain mutant which is temperature sensitive for cellular transformation: interactions with GTPase-activating protein and NF-1. | 1991 Jun |
1 |
| 46 |
2116014 | Identification of a nucleotide exchange-promoting activity for p21ras. | 1990 Aug |
1 |
| 47 |
2120590 | Co-capping of ras proteins with surface immunoglobulins in B lymphocytes. | 1990 Sep 27 |
1 |
| 48 |
2121270 | Unique guanine nucleotide binding properties of the human placental GTP-binding protein Gp. | 1990 Jul 31 |
1 |
| 49 |
2199064 | Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules. | 1990 Aug 10 |
1 |
| 50 |
2491843 | Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins. | 1989 Jan 5 |
1 |