Cysteine

HRas proto-oncogene, GTPase ; Homo sapiens







39 Article(s)
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1 34738101 Multimerization of small G-protein H-Ras induced by chemical modification at hyper variable region with caged compound. 2022 Feb 21 1
2 33452674 15-Deoxy-Δ12,14 -prostaglandin J2 binds and inactivates STAT3 via covalent modification of cysteine 259 in H-Ras-transformed human breast epithelial cells. 2021 Mar 2
3 28648093 S-Nitrosylation of Ras Mediates Nitric Oxide-Dependent Post-Injury Neurogenesis in a Seizure Model. 2018 Jan 1 1
4 29686295 Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells. 2018 Apr 23 1
5 28179458 Individual S-acylated cysteines differentially contribute to H-Ras endomembrane trafficking and acylation/deacylation cycles. 2017 Apr 1 2
6 27624845 Generation of self-clusters of galectin-1 in the farnesyl-bound form. 2016 Sep 14 1
7 25902334 Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S. 2015 1
8 25452233 [Establishment of a novel therapeutic strategy for heart failure based on the mechanism underlying maintenance of redox homeostasis by reactive sulfur species]. 2014 2
9 22894707 S-nitrosoglutathione and endothelial nitric oxide synthase-derived nitric oxide regulate compartmentalized ras S-nitrosylation and stimulate cell proliferation. 2013 Jan 20 1
10 23123410 Glutathiolated Ras: characterization and implications for Ras activation. 2013 Apr 1
11 22550136 Evidence for the importance of OxPAPC interaction with cysteines in regulating endothelial cell function. 2012 Jul 1
12 21103953 S-nitrosylation decreases the adsorption of H-Ras in lipid bilayer and changes intrinsic catalytic activity. 2011 Apr 3
13 21253588 The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways. 2011 Jan 6 5
14 18325324 The nitric oxide-sensitive p21Ras-ERK pathway mediates S-nitrosoglutathione-induced apoptosis. 2008 May 16 1
15 17236767 Pharmacophore mapping of diverse classes of farnesyltransferase inhibitors. 2007 Mar 15 1
16 17320764 Quantification of oxidative posttranslational modifications of cysteine thiols of p21ras associated with redox modulation of activity using isotope-coded affinity tags and mass spectrometry. 2007 Mar 15 1
17 17489560 Modification and activation of Ras proteins by electrophilic prostanoids with different structure are site-selective. 2007 Jun 5 1
18 16415107 S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells. 2006 Mar 3
19 16488996 Ras and its signals diffuse through the cell on randomly moving nanoparticles. 2006 Feb 15 1
20 16824054 Nonconventional trafficking of Ras associated with Ras signal organization. 2006 Sep 1
21 16024806 Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. 2005 Aug 2
22 16138855 Novel thioester reagents afford efficient and specific S-acylation of unprotected peptides under mild conditions in aqueous solution. 2005 Oct 1
23 14979728 Mechanism of p21Ras S-nitrosylation and kinetics of nitric oxide-mediated guanine nucleotide exchange. 2004 Mar 2 1
24 12684535 The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras. 2003 Apr 15 2
25 10815773 Conformational analysis of a farnesyltransferase peptide inhibitor, CVIM. 2000 May 1
26 10607402 Display of Ras on filamentous phage through cysteine replacement. 1999 Dec 8
27 9312159 Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine. 1997 Oct 3 1
28 8628998 Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS. 1996 Feb 9 1
29 8798525 Purification of a protein palmitoyltransferase that acts on H-Ras protein and on a C-terminal N-Ras peptide. 1996 Sep 20 1
30 7586199 Mutagenicity of a unique 8-oxoguanine in a human Ha-ras sequence in mammalian cells. 1995 Nov 1
31 8175645 Design and structural requirements of potent peptidomimetic inhibitors of p21ras farnesyltransferase. 1994 Apr 29 2
32 8251476 Conformation of a heptapeptide substrate bound to protein farnesyltransferase. 1993 Nov 30 1
33 8407887 Potent inhibition of human tumor p21ras farnesyltransferase by A1A2-lacking p21ras CA1A2X peptidomimetics. 1993 Oct 5 2
34 1740442 rab GTP-binding proteins with three different carboxyl-terminal cysteine motifs are modified in vivo by 20-carbon isoprenoids. 1992 Feb 25 1
35 2018975 Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit. 1991 May 3 1
36 2123808 Posttranslational modification of proteins by isoprenoids in mammalian cells. 1990 Dec 1
37 2183224 Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation. 1990 Apr 1
38 3045729 Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region. 1988 Aug 1
39 3144694 Preferential and novel activation of H-ras in human bladder carcinomas. 1988 1