| 1 |
35246464 | Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes. | 2022 May |
1 |
| 2 |
35583123 | Methysticin Acts as a Mechanism-Based Inactivator of Cytochrome P450 2C9. | 2022 Jun 20 |
2 |
| 3 |
29119333 | Physiologically Based Pharmacokinetic Modelling of Cytochrome P450 2C9-Related Tolbutamide Drug Interactions with Sulfaphenazole and Tasisulam. | 2018 Jun |
1 |
| 4 |
26655108 | Comparison of enzyme kinetics of warfarin analyzed by LC-MS/MS QTrap and differential mobility spectrometry. | 2016 Jan 1 |
1 |
| 5 |
26877175 | On-line coupling of immobilized cytochrome P450 microreactor and capillary electrophoresis: A promising tool for drug development. | 2016 Mar 11 |
1 |
| 6 |
25656643 | Resveratrol alters human endothelial cells redox state and causes mitochondrial-dependent cell death. | 2015 Apr |
1 |
| 7 |
25804257 | Nanoscale electron transport measurements of immobilized cytochrome P450 proteins. | 2015 Apr 17 |
1 |
| 8 |
26138612 | In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. | 2015 Sep |
1 |
| 9 |
24519941 | Cytochrome P450 2C epoxygenases mediate photochemical stress-induced death of photoreceptors. | 2014 Mar 21 |
2 |
| 10 |
23504614 | Coumaric acid induces mitochondrial damage and oxidative-mediated cell death of human endothelial cells. | 2013 Sep |
1 |
| 11 |
24174816 | Inhibitory effect of mitragynine on human cytochrome P450 enzyme activities. | 2013 Oct |
1 |
| 12 |
24329780 | Sulfaphenazole and α-naphthoflavone attenuate the metabolism of the synthetic cannabinoids JWH-018 and AM2201 found in K2/spice. | 2013 Mar |
2 |
| 13 |
22311023 | Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.). | 2012 Jun |
1 |
| 14 |
22447115 | Increased expression of drug-metabolizing enzymes in human hepatocarcinoma FLC-4 cells cultured on micro-space cell culture plates. | 2012 |
1 |
| 15 |
21532165 | In vitro characterization of the cytochrome P450 isoforms involved in the metabolism of 6-methoxy-2-napthylacetic acid, an active metabolite of the prodrug nabumetone. | 2011 |
1 |
| 16 |
19717402 | A sulfaphenazole-sensitive EDHF opposes platelet-endothelium interactions in vitro and in the hamster microcirculation in vivo. | 2010 Feb 1 |
1 |
| 17 |
19883715 | Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity. | 2010 Jan |
1 |
| 18 |
20022989 | The sulfaphenazole-sensitive pathway acts as a compensatory mechanism for impaired nitric oxide availability in patients with primary hyperparathyroidism. Effect of surgical treatment. | 2010 Feb |
1 |
| 19 |
19022226 | Investigations on the cytochrome P450 (CYP) isoenzymes involved in the metabolism of the designer drugs N-(1-phenyl cyclohexyl)-2-ethoxyethanamine and N-(1-phenylcyclohexyl)-2-methoxyethanamine. | 2009 Feb 1 |
1 |
| 20 |
19289643 | Effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients. | 2009 Mar 31 |
2 |
| 21 |
18356043 | Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone. | 2008 May |
1 |
| 22 |
18669935 | Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans. | 2008 Oct |
1 |
| 23 |
18787056 | Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro. | 2008 Dec |
1 |
| 24 |
17572144 | Cytochrome P450 2C9 is involved in flow-dependent vasodilation of peripheral conduit arteries in healthy subjects and in patients with chronic heart failure. | 2007 Aug |
1 |
| 25 |
16415119 | Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450. | 2006 Apr |
1 |
| 26 |
16505204 | Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling. | 2006 Apr |
1 |
| 27 |
16698161 | Polysaccharide peptides from COV-1 strain of Coriolus versicolor inhibit tolbutamide 4-hydroxylation in the rat in vitro and in vivo. | 2006 Aug |
1 |
| 28 |
16875977 | Identification of a cytochrome P450 2C9-derived endothelium-derived hyperpolarizing factor in essential hypertensive patients. | 2006 Aug 1 |
4 |
| 29 |
17097122 | Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytes. | 2006 Dec 15 |
1 |
| 30 |
15569819 | Cytochrome P4502C9-derived epoxyeicosatrienoic acids induce the expression of cyclooxygenase-2 in endothelial cells. | 2005 Feb |
2 |
| 31 |
15764717 | Detection of a novel reactive metabolite of diclofenac: evidence for CYP2C9-mediated bioactivation via arene oxides. | 2005 Jun |
4 |
| 32 |
15840038 | Nitric oxide- and EDHF-mediated arteriolar tone in uremia is unaffected by selective inhibition of vascular cytochrome P450 2C9. | 2005 May |
1 |
| 33 |
15843491 | Identification of cytochrome P450 and arylamine N-acetyltransferase isoforms involved in sulfadiazine metabolism. | 2005 Jul |
2 |
| 34 |
15855725 | Role of human liver cytochrome P450 2C9 in the metabolism of a novel alpha4beta1/alpha4beta7 dual antagonist, TR-14035. | 2005 Apr |
1 |
| 35 |
16291720 | Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis. | 2005 Dec 1 |
1 |
| 36 |
14662709 | Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease. | 2004 Jan 20 |
1 |
| 37 |
14977868 | In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily. | 2004 Mar |
2 |
| 38 |
15304426 | The involvement of CYP3A4 and CYP2C9 in the metabolism of 17 alpha-ethinylestradiol. | 2004 Nov |
1 |
| 39 |
15370961 | Stereoselective glucuronidation and hydroxylation of etodolac by UGT1A9 and CYP2C9 in man. | 2004 May |
1 |
| 40 |
12464247 | Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid. | 2003 Jan 1 |
3 |
| 41 |
12586744 | Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR). | 2003 Apr |
2 |
| 42 |
12826020 | Baseline blood flow and bradykinin-induced vasodilator responses in the human forearm are insensitive to the cytochrome P450 2C9 (CYP2C9) inhibitor sulphaphenazole. | 2003 Oct |
1 |
| 43 |
14684755 | Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. | 2003 Dec |
1 |
| 44 |
11867622 | Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1. | 2002 May 3 |
1 |
| 45 |
11950794 | Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes. | 2002 May |
1 |
| 46 |
11964373 | Dynamic modulation of interendothelial gap junctional communication by 11,12-epoxyeicosatrienoic acid. | 2002 Apr 19 |
1 |
| 47 |
12180536 | The N-demethylation of the doxepin isomers is mainly catalyzed by the polymorphic CYP2C19. | 2002 Jul |
1 |
| 48 |
12236850 | Involvement of CYP2C9 and UGT2B7 in the metabolism of zaltoprofen, a nonsteroidal anti-inflammatory drug, and its lack of clinically significant CYP inhibition potential. | 2002 Sep |
1 |
| 49 |
11139472 | Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries. | 2001 Jan 19 |
2 |
| 50 |
11181505 | Metabolic characterization of the major human small intestinal cytochrome p450s. | 2001 Mar |
2 |