Mephenytoin

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







15 Article(s)
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Pub. Year
#Total Relationships
1 25760542 Genetic polymorphism of cynomolgus and rhesus macaque CYP2C9. 2015 Feb 2
2 23241944 Human pharmacogenetic analysis in chimeric mice with 'humanized livers'. 2013 Feb 1
3 22943175 In-vitro metabolism of glycyrrhetinic acid by human and rat liver microsomes and its interactions with six CYP substrates. 2012 Oct 1
4 15304427 Cytochrome P450 3A4 is the major enzyme involved in the metabolism of the substance P receptor antagonist aprepitant. 2004 Nov 1
5 12637241 mRNA and protein expression of dog liver cytochromes P450 in relation to the metabolism of human CYP2C substrates. 2003 Mar 1
6 12900870 Capillary electrophoresis to assess drug metabolism induced in vitro using single CYP450 enzymes (Supersomes): application to the chiral metabolism of mephenytoin and methadone. 2003 Aug 1
7 11329260 Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9. 2001 Feb 20 1
8 10901692 CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone. 2000 Aug 1
9 10383917 Sertraline N-demethylation is catalyzed by multiple isoforms of human cytochrome P-450 in vitro. 1999 Jul 1
10 9578596 Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations. 1998 May 1 2
11 9698292 Human N-demethylation of (S)-mephenytoin by cytochrome P450s 2C9 and 2B6. 1998 Aug 1
12 8333835 Gene structure and upstream regulatory regions of human CYP2C9 and CYP2C18. 1993 Jul 15 2
13 8454228 [Genetic polymorphism in human drug metabolism]. 1993 Feb 1
14 1917894 Cytochrome P-450 human-2 (P-450IIC9) in mephenytoin hydroxylation polymorphism in human livers: differences in substrate and stereoselectivities among microheterogeneous P-450IIC species expressed in yeasts. 1991 May 1
15 2827463 Human cytochrome P-450 PB-1: a multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10. 1988 Jan 1