Benzbromarone

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







14 Article(s)
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1 33132262 [Pharmacological properties and clinical efficacy of dotinurad (URECE® tablets), a novel hypouricemic agent]. 2020 1
2 29100760 Comparative study on the interaction between 3 CYP2C9 allelic isoforms and benzbromarone by using LC-MS/MS method. 2017 Dec 1 12
3 26693855 Inactivation of CYP3A4 by Benzbromarone in Human Liver Microsomes. 2016 1
4 23932726 Frequency of CYP2C9 polymorphisms in Polynesian people and potential relevance to management of gout with benzbromarone. 2014 Mar 3
5 24594849 The curious case of benzbromarone: insight into super-inhibition of cytochrome P450. 2014 3
6 23229783 Cytotoxic effects of benzbromarone and its 1'-hydroxy metabolite in human hepatocarcinoma FLC4 cells cultured on micro-space cell culture plates. 2013 1
7 20962433 Benzbromarone pharmacokinetics and pharmacodynamics in different cytochrome P450 2C9 genotypes. 2010 5
8 18636784 A benefit-risk assessment of benzbromarone in the treatment of gout. Was its withdrawal from the market in the best interest of patients? 2008 3
9 16815961 Amiodarone analog-dependent effects on CYP2C9-mediated metabolism and kinetic profiles. 2006 Oct 2
10 15843486 Three-dimensional quantitative structure-activity relationship analysis of cytochromes p450: effect of incorporating higher-affinity ligands and potential new applications. 2005 Jul 2
11 15955872 CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant. 2005 Sep 7
12 15170332 Quantitative binding models for CYP2C9 based on benzbromarone analogues. 2004 Jun 8 3
13 12814975 A new class of CYP2C9 inhibitors: probing 2C9 specificity with high-affinity benzbromarone derivatives. 2003 Jul 1
14 10613612 Potentiation of anticoagulant effect of warfarin caused by enantioselective metabolic inhibition by the uricosuric agent benzbromarone. 1999 Dec 3