Proline

SRC proto-oncogene, non-receptor tyrosine kinase ; Homo sapiens







72 Article(s)
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1 33837725 Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion. 2021 Jan-Jun 1
2 34582006 Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics. 2021 Dec 1
3 34688656 Mechanistic roles of tyrosine phosphorylation in reversible amyloids, autoinhibition, and endosomal membrane association of ALIX. 2021 Nov 1
4 30824759 Src in endosomal membranes promotes exosome secretion and tumor progression. 2019 Mar 1 2
5 29928795 EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains. 2018 Jul 17 1
6 28049762 The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection. 2017 Jan 3 1
7 29254203 Inhibition of STAT3/VEGF/CDK2 axis signaling is critically involved in the antiangiogenic and apoptotic effects of arsenic herbal mixture PROS in non-small lung cancer cells. 2017 Nov 24 2
8 27227417 Correction to Multiple Src Homology 3 Binding to the Ubiquitin Ligase Itch Conserved Proline-Rich Region. 2016 Jun 7 1
9 27480221 Imatinib binding to human c-Src is coupled to inter-domain allostery and suggests a novel kinase inhibition strategy. 2016 Aug 2 1
10 26613292 Multiple Src Homology 3 Binding to the Ubiquitin Ligase Itch Conserved Proline-Rich Region. 2015 Dec 22 2
11 24556574 3D domain swapping in a chimeric c-Src SH3 domain takes place through two hinge loops. 2014 Apr 2
12 24582589 Overexpression of atypical protein kinase C in HeLa cells facilitates macropinocytosis via Src activation. 2014 Jun 2
13 24706440 The ROR1 pseudokinase diversifies signaling outputs in MET-addicted cancer cells. 2014 Nov 15 1
14 25031324 Expanding the proteome of an RNA virus by phosphorylation of an intrinsically disordered viral protein. 2014 Aug 29 1
15 25490095 Electrostatic effects in the folding of the SH3 domain of the c-Src tyrosine kinase: pH-dependence in 3D-domain swapping and amyloid formation. 2014 1
16 23169783 Structural framework of c-Src activation by integrin β3. 2013 Jan 24 1
17 21236256 Actin filament associated protein mediates c-Src related SRE/AP-1 transcriptional activation. 2011 Feb 4 2
18 22078467 Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility. 2011 Nov 13 1
19 20109515 Synthesis and evaluation of conformationally constrained peptide analogues as the Src SH3 domain binding ligands. 2010 Sep 1
20 20173116 Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit. 2010 Apr 22 1
21 20525694 The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme. 2010 Jul 30 1
22 20638934 Novel KCNA5 mutation implicates tyrosine kinase signaling in human atrial fibrillation. 2010 Sep 2
23 17700527 Diacylglycerol kinase-alpha phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility. 2008 Feb 7 2
24 18083027 In silico screening and biological evaluation of inhibitors of Src-SH3 domain interaction with a proline-rich ligand. 2008 Feb 1 3
25 18342899 Sex-steroid hormones and EGF signalling in breast and prostate cancer cells: targeting the association of Src with steroid receptors. 2008 Oct 2
26 18571832 PELP1--a novel estrogen receptor-interacting protein. 2008 Aug 13 1
27 17178840 Deciphering the cross talk between hnRNP K and c-Src: the c-Src activation domain in hnRNP K is distinct from a second interaction site. 2007 Mar 4
28 17189480 The SH3 domain of a M7 interacts with its C-terminal proline-rich region. 2007 Feb 1
29 17283076 Phosphorylation of a Wiscott-Aldrich syndrome protein-associated signal complex is critical in osteoclast bone resorption. 2007 Mar 30 1
30 17418139 Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: loop flexibility and amyloid aggregation. 2007 May 1 1
31 17038311 Proline-rich motifs in the parathyroid hormone (PTH)/PTH-related protein receptor C terminus mediate scaffolding of c-Src with beta-arrestin2 for ERK1/2 activation. 2006 Dec 15 3
32 17094785 Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl. 2006 Dec 7
33 15557335 Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities. 2005 Feb 4 1
34 15615649 Tau and src family tyrosine kinases. 2005 Jan 3 1
35 15723349 Solution NMR structure of the SH3 domain of human nephrocystin and analysis of a mutation-causing juvenile nephronophthisis. 2005 May 1 1
36 15784259 The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity. 2005 Apr 15 1
37 15872089 Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity. 2005 Jul 1
38 15994299 Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation. 2005 Sep 9 1
39 14670955 Src homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors. 2004 Feb 27 1
40 15217616 Molecular recognition properties of FN3 monobodies that bind the Src SH3 domain. 2004 Jun 2
41 12473651 Characterization of a novel negative regulator (DOC-2/DAB2) of c-Src in normal prostatic epithelium and cancer. 2003 Feb 28 2
42 12529254 Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cells. 2003 Feb 1
43 12612073 Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells. 2003 Mar 1
44 11943772 Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling. 2002 Jun 14 2
45 11964172 Differential effect of the inhibition of Grb2-SH3 interactions in platelet activation induced by thrombin and by Fc receptor engagement. 2002 May 1 1
46 12023880 Interaction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domains. 2002 Jun 1 1
47 12163161 The proline rich region of the Tec homology domain of ITK regulates its activity. 2002 Aug 14 1
48 12223544 Phosphorylation-dependent and phosphorylation-independent modes of modulation of shaker family voltage-gated potassium channels by SRC family protein tyrosine kinases. 2002 Sep 15 1
49 11509578 mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation. 2001 Oct 19 2
50 11518702 The ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK. 2001 Nov 9 1