| 1 |
35506586 | Orai2 channel regulates prostaglandin E2 production in TNFα/IL1α-stimulated astrocytes. | 2022 May 4 |
1 |
| 2 |
33934781 | A rapid and sensitive method for characterization and quantification of polyglycerol esters by supercritical fluid chromatography coupled to high-resolution mass spectrometry (SFC-HRMS). | 2021 Aug 1 |
2 |
| 3 |
28333263 | Loss of luteotropic prostaglandin E plays an important role in the regulation of luteolysis in women. | 2017 May 1 |
2 |
| 4 |
23218602 | Fragment-based discovery of novel and selective mPGES-1 inhibitors Part 1: identification of sulfonamido-1,2,3-triazole-4,5-dicarboxylic acid. | 2013 Jan 1 |
1 |
| 5 |
21743491 | Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis. | 2012 Feb 16 |
1 |
| 6 |
21905007 | Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice. | 2012 Jan |
1 |
| 7 |
22204820 | All-trans retinoic acid up-regulates Prostaglandin-E Synthase expression in human macrophages. | 2012 Jun |
3 |
| 8 |
22337655 | Lead discovery for microsomal prostaglandin E synthase using a combination of high-throughput fluorescent-based assays and RapidFire mass spectrometry. | 2012 Jun |
1 |
| 9 |
22356188 | Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). | 2012 Mar 20 |
1 |
| 10 |
22763855 | Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. | 2012 Sep |
1 |
| 11 |
22895459 | High-precision, room temperature screening assay for inhibitors of microsomal prostaglandin E synthase-1. | 2012 Dec |
1 |
| 12 |
21561373 | A facilitated approach to evaluate the inhibitor mode and potency of compounds targeting microsomal prostaglandin e synthase-1. | 2011 Oct |
1 |
| 13 |
21589857 | Hypoxia and prostaglandin E receptor 4 signalling pathways synergise to promote endometrial adenocarcinoma cell proliferation and tumour growth. | 2011 May 12 |
1 |
| 14 |
21907186 | Induction of human microsomal prostaglandin E synthase 1 by activated oncogene RhoA GTPase in A549 human epithelial cancer cells. | 2011 Sep 30 |
1 |
| 15 |
22023034 | Identification and development of mPGES-1 inhibitors: where we are at? | 2011 Nov |
1 |
| 16 |
19788928 | Prostaglandin E2 at new glance: novel insights in functional diversity offer therapeutic chances. | 2010 Feb |
2 |
| 17 |
20042640 | Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis. | 2010 Mar |
1 |
| 18 |
20067770 | Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor. | 2010 May 15 |
1 |
| 19 |
20497297 | Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer. | 2010 Jul |
4 |
| 20 |
20605783 | Identification of key residues determining species differences in inhibitor binding of microsomal prostaglandin E synthase-1. | 2010 Sep 17 |
1 |
| 21 |
18802697 | High expression of PGE2 enzymatic pathways in cervical (pre)neoplastic lesions and functional consequences for antigen-presenting cells. | 2009 Apr |
1 |
| 22 |
19035518 | Association between adenomatosis polyposis coli functional status and microsomal prostaglandin E synthase-1 expression in colorectal cancer. | 2009 May |
1 |
| 23 |
19115247 | HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activity. | 2009 Feb 15 |
1 |
| 24 |
19846775 | Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells. | 2009 Nov 3 |
3 |
| 25 |
18682561 | Structural basis for induced formation of the inflammatory mediator prostaglandin E2. | 2008 Aug 12 |
1 |
| 26 |
18715952 | Tumor-growth-promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets. | 2008 Oct |
2 |
| 27 |
19017494 | Expression and purification of human mPGES-1 in E. coli and identification of inhibitory compounds from a drug-library. | 2008 Nov 30 |
1 |
| 28 |
17014826 | Involvement of early growth response gene 1 in the modulation of microsomal prostaglandin E synthase 1 by epigallocatechin gallate in A549 human pulmonary epithelial cells. | 2007 Jan 1 |
1 |
| 29 |
17105783 | Expression and regulation of prostaglandin E synthase isoforms in human myometrium with labour. | 2007 Jan |
1 |
| 30 |
17403097 | Microsomal prostaglandin E synthase-1, which is not coupled to a particular cyclooxygenase isoenzyme, is essential for prostaglandin E(2) biosynthesis in vascular smooth muscle cells. | 2007 Jul |
1 |
| 31 |
17629358 | Roles of prostaglandin synthesis in excitotoxic brain diseases. | 2007 Jul-Sep |
1 |
| 32 |
16195422 | Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha. | 2006 Feb |
1 |
| 33 |
16495511 | 15-deoxy-Delta12,14-prostaglandin J2 inhibits the expression of microsomal prostaglandin E synthase type 2 in colon cancer cells. | 2006 May |
2 |
| 34 |
16533161 | Prostaglandin E synthase: a novel drug target for inflammation and cancer. | 2006 |
1 |
| 35 |
16891468 | Microsomal prostaglandin E synthase-1 regulates human glioma cell growth via prostaglandin E(2)-dependent activation of type II protein kinase A. | 2006 Jul |
1 |
| 36 |
15744024 | Expression and contribution of three different isoforms of prostaglandin E synthase in the bovine endometrium. | 2005 Jul |
1 |
| 37 |
15854652 | Crystal structure and possible catalytic mechanism of microsomal prostaglandin E synthase type 2 (mPGES-2). | 2005 May 20 |
1 |
| 38 |
14722058 | Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1. | 2004 Mar 26 |
1 |
| 39 |
14987993 | PI 3-kinase and MAP kinase regulate bradykinin induced prostaglandin E(2) release in human pulmonary artery by modulating COX-2 activity. | 2004 Feb 27 |
2 |
| 40 |
15188353 | Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synovium. | 2004 Jun |
1 |
| 41 |
15457451 | Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways. | 2004 Sep |
1 |
| 42 |
12519887 | Expression and localization of prostaglandin E synthase isoforms in human fetal membranes in term and preterm labor. | 2003 Jan |
2 |
| 43 |
12605868 | Continuous spectrophotometric assay amenable to 96-well plate format for prostaglandin E synthase activity. | 2003 Feb 15 |
1 |
| 44 |
14520691 | Expression of microsomal prostaglandin E synthase-1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines. | 2003 Nov 20 |
1 |
| 45 |
11809691 | Cyclooxygenase-1 is up-regulated in cervical carcinomas: autocrine/paracrine regulation of cyclooxygenase-2, prostaglandin e receptors, and angiogenic factors by cyclooxygenase-1. | 2002 Jan 15 |
1 |
| 46 |
11882577 | Trophic effects of the cyclooxygenase-2 product prostaglandin E(2) in cardiac myocytes. | 2002 Feb |
1 |
| 47 |
12145315 | Cytoplasmic prostaglandin E2 synthase is dominantly expressed in cultured KAT-50 thyrocytes, cells that express constitutive prostaglandin-endoperoxide H synthase-2. Basis for low protaglandin E2 production. | 2002 Sep 27 |
1 |
| 48 |
12414902 | Expression of prostaglandin I(2) synthase, but not prostaglandin E synthase, changes in myometrium of women at term pregnancy. | 2002 Nov |
1 |
| 49 |
11448962 | Molecular cloning and induction of bovine prostaglandin E synthase by gonadotropins in ovarian follicles prior to ovulation in vivo. | 2001 Sep 7 |
1 |
| 50 |
7516968 | Misoprostol stimulates leukocyte cyclic adenosine 3',5' monophosphate production and synergizes with colchicine: novel combination of established drugs may boost anti-inflammatory potential. | 1994 Jun |
1 |