ARQ 197

cytochrome P450 family 2 subfamily C member 19 ; Homo sapiens







5 Article(s)
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Title
Pub. Year
#Total Relationships
1 26899628 Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib. 2016 Nov 4
2 27991432 The effect of proton pump inhibitors on the CYP2C19 enzyme activity evaluated by the pantoprazole-13C breath test in GERD patients: clinical relevance for personalized medicine. 2016 Dec 17 1
3 25711511 Phase I study of tivantinib in Japanese patients with advanced hepatocellular carcinoma: Distinctive pharmacokinetic profiles from other solid tumors. 2015 May 1
4 23413279 The effect of CYP2C19 polymorphism on the safety, tolerability, and pharmacokinetics of tivantinib (ARQ 197): results from a phase I trial in advanced solid tumors. 2013 Jun 2
5 24169346 CYP2C19 genotype-based phase I studies of a c-Met inhibitor tivantinib in combination with erlotinib, in advanced/metastatic non-small cell lung cancer. 2013 Nov 26 3