Leukotrienes

leukotriene A4 hydrolase ; Homo sapiens







28 Article(s)
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1 33658385 Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone. 2021 Mar 9 2
2 30745237 Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase. 2019 Apr 18 1
3 29890138 Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method. 2018 Oct 7 1
4 27914004 Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs. 2017 Mar 1
5 28005436 Novel leukotriene biosynthesis inhibitors (2012-2016) as anti-inflammatory agents. 2017 May 1
6 28065501 Synthesis, docking, cytotoxicity, and LTA4H inhibitory activity of new gingerol derivatives as potential colorectal cancer therapy. 2017 Feb 1 1
7 27990118 Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies. 2016 1
8 24366255 Expression analysis of leukotriene-inflammatory gene interaction network in patients with coronary artery disease. 2014 2
9 25211287 Expression of leukotriene biosynthetic enzymes in tonsillar tissue of children with obstructive sleep apnea: a prospective nonrandomized study. 2014 Oct 2
10 23851339 A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity. 2013 Oct 15 2
11 25215090 Association of ALOX5, LTA4H and LTC4S gene polymorphisms with ischemic stroke risk in a cohort of Chinese in east China. 2013 1
12 22206291 The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers. 2011 Dec 29 1
13 20067482 The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos. 2010 Apr 2
14 20810156 ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos. 2010 Oct 3
15 19077707 Pharmacogenetics of asthma. 2009 Jan 1
16 19130089 Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. 2009 Mar 2
17 19618939 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. 2009 Aug 13 1
18 24422736 Genetic influences on response to asthma pharmacotherapy. 2008 Sep 1
19 16635437 Role of FLAP and PDE4D in myocardial infarction and stroke: target discovery and future treatment options. 2006 May 1
20 16733792 Expression of 5-lipoxygenase in specialized epithelial cells of nasopharyngeal-associated lymphoid tissue. 2005 Oct 1
21 12765316 Leukotriene synthesis is increased by transcriptional up-regulation of 5-lipoxygenase, leukotriene A4 hydrolase, and leukotriene C4 synthase in asthmatic children. 2003 Apr 1
22 11175901 Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation. 2001 Feb 1
23 10940725 Reciprocal regulation of LTA(4) hydrolase expression in human monocytes by gamma-interferon and interleukins 4 and 13: potential relevance to leukotriene regulation in glomerular disease. 2000 Jul-Oct 1
24 10320802 Alteration of human leukotriene A4 hydrolase activity after site-directed mutagenesis: serine-415 is a regulatory residue. 1999 May 18 2
25 9751098 Leukotriene A4 hydrolase and leukotriene C4 synthase activities in human chondrocytes: transcellular biosynthesis of Leukotrienes during granulocyte-chondrocyte interaction. 1998 Sep 1
26 7649404 Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases. 1995 Aug 1
27 7938075 5-Lipoxygenase: enzyme expression and regulation of activity. 1994 Jul 1
28 1357660 Leukotriene A4 hydrolase: abrogation of the peptidase activity by mutation of glutamic acid-296. 1992 Oct 1 2