Serine

appetite-regulating hormone ; Capra hircus







32 Article(s)
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1 30542007 Decreased Plasma Octanoylated Ghrelin Levels in Mice by Oleanolic Acid. 2019 Jan 1 1
2 30626708 Ghrelin octanoylation by ghrelin O-acyltransferase: Unique protein biochemistry underlying metabolic signaling. 2019 Feb 28 1
3 28846466 Identification and Characterization of a New Series of Ghrelin O-Acyl Transferase Inhibitors. 2018 Feb 1
4 29063591 Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. 2018 Jan 2
5 29713145 Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK-mTOR pathway. 2018 2
6 29738973 Functional group and stereochemical requirements for substrate binding by ghrelin O-acyltransferase revealed by unnatural amino acid incorporation. 2018 Sep 2
7 27489223 Ghrelin O-acyltransferase (GOAT), a specific enzyme that modifies ghrelin with a medium-chain fatty acid. 2016 Oct 1
8 28003581 Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. 2016 1
9 25337923 The level of circulating octanoate does not predict ghrelin O-acyl transferase (GOAT)-mediated acylation of ghrelin during fasting. 2015 Jan 2
10 25562443 Structure-activity analysis of human ghrelin O-acyltransferase reveals chemical determinants of ghrelin selectivity and acyl group recognition. 2015 Feb 3 2
11 25805927 Ghrelin-ghrelin O-acyltransferase system in the pathogenesis of nonalcoholic fatty liver disease. 2015 Mar 21 1
12 26028164 Knockdown of central ghrelin O-acyltransferase by vivo-morpholino reduces body mass of rats fed a high-fat diet. 2015 Aug 3
13 23453974 A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase. 2013 Jun 1 1
14 23652388 Discovery of ghrelin o-acyltransferase. 2013 1
15 23652399 Ghrelin function in insulin release and glucose metabolism. 2013 3
16 23770219 Changes in the ghrelin hormone pathway maybe part of an unusual gastric system in monotremes. 2013 Sep 15 2
17 22523666 Recent advances in potential clinical application of ghrelin in obesity. 2012 1
18 22975051 From ghrelin to ghrelin's O-acyl transferase. 2012 2
19 22975052 Enzymatic characterization of GOAT, ghrelin O-acyltransferase. 2012 5
20 21035823 Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa. 2011 May 2
21 21340583 The ghrelin/GOAT/GHS-R system and energy metabolism. 2011 Sep 2
22 21625987 Molecular cloning and expression analysis of porcine ghrelin o-acyltransferase. 2011 Oct 1
23 20798855 Ghrelin cells in the gastrointestinal tract. 2010 2
24 21063108 Modulation of ghrelin O-acyltransferase expression in pancreatic islets. 2010 1
25 21097901 Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor. 2010 Dec 17 2
26 19501572 Ghrelin O-acyltransferase (GOAT) has a preference for n-hexanoyl-CoA over n-octanoyl-CoA as an acyl donor. 2009 Aug 14 2
27 19628676 Production of n-octanoyl-modified ghrelin in cultured cells requires prohormone processing protease and ghrelin O-acyltransferase, as well as n-octanoic acid. 2009 Nov 2
28 20038570 Ghrelin gene products and the regulation of food intake and gut motility. 2009 Dec 4
29 18267071 Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. 2008 Feb 8 3
30 18316023 Ghrelin gets its GOAT. 2008 Mar 1
31 18443287 Ghrelin octanoylation mediated by an orphan lipid transferase. 2008 Apr 29 2
32 18606462 Introducing GOAT: a target for obesity and anti-diabetic drugs? 2008 Aug 1