| 1 |
21606248 | IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii. | 2011 Jul 1 |
1 |
| 2 |
16920960 | CD40/CD154 interactions are required for the optimal maturation of skin-derived APCs and the induction of helminth-specific IFN-gamma but not IL-4. | 2006 Sep 1 |
1 |
| 3 |
15034023 | Genome-wide analysis of molecular changes in IL-12-induced control of mammary carcinoma via IFN-gamma-independent mechanisms. | 2004 Apr 1 |
1 |
| 4 |
15555529 | Essential role for the p40 subunit of interleukin-12 in neutrophil-mediated early host defense against pulmonary infection with Streptococcus pneumoniae: involvement of interferon-gamma. | 2004 Nov |
1 |
| 5 |
14500667 | IFN-gamma-independent effects of IL-12 during intestinal nematode infection. | 2003 Oct 1 |
1 |
| 6 |
12471132 | Protection against Helicobacter pylori infection following immunization is IL-12-dependent and mediated by Th1 cells. | 2002 Dec 15 |
1 |
| 7 |
11343214 | Combined interleukin-12 and topical chemotherapy for established Leishmaniasis drastically reduces tissue parasitism and relapses in susceptible mice. | 2001 Jun 1 |
2 |
| 8 |
11592087 | Different requirements for alpha-galactosylceramide and recombinant IL-12 antitumor activity in the treatment of C-26 colon carcinoma hepatic metastases. | 2001 Oct |
2 |
| 9 |
11698474 | Inability of IL-12 to down-regulate IgE synthesis due to defective production of IFN-gamma in atopic NC/Nga mice. | 2001 Nov 15 |
1 |
| 10 |
10679069 | Exclusive Th2 primary effector function in spleens but mixed Th1/Th2 function in lymph nodes of murine neonates. | 2000 Mar 1 |
1 |
| 11 |
10706693 | Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile. | 2000 Mar 15 |
1 |
| 12 |
10882414 | Failure of rIL-12 administration to inhibit established IgE responses in vivo is associated with enhanced IL-4 synthesis by non-B/non-T cells. | 2000 Jul |
1 |
| 13 |
10092824 | Endotoxin fails to induce IFN-gamma in endotoxin-tolerant mice: deficiencies in both IL-12 heterodimer production and IL-12 responsiveness. | 1999 Mar 15 |
1 |
| 14 |
10457211 | Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling to downregulate T-helper 2 responses. | 1999 Aug |
1 |
| 15 |
10510362 | Role of IL-12 in the induction and potentiation of IFN-gamma in response to bacillus Calmette-Guérin. | 1999 Oct 15 |
1 |
| 16 |
9526842 | Expression of IL-12 in CNS and lymphoid organs of mice with experimental allergic encephalitis. | 1998 Feb |
1 |
| 17 |
9590248 | Localization and regulation of IFN-gamma production within the granulomas of murine schistosomiasis in IL-4-deficient and control mice. | 1998 May 15 |
1 |
| 18 |
9754570 | In the absence of IL-12, the induction of Th1-mediated protective immunity by the attenuated schistosome vaccine is impaired, revealing an alternative pathway with Th2-type characteristics. | 1998 Sep |
1 |
| 19 |
8977200 | Down-regulation of IL-12, not a shift from a T helper-1 to a T helper-2 phenotype, is responsible for impaired IFN-gamma production in mammary tumor-bearing mice. | 1997 Jan 1 |
1 |
| 20 |
9126973 | An ovalbumin-IL-12 fusion protein is more effective than ovalbumin plus free recombinant IL-12 in inducing a T helper cell type 1-dominated immune response and inhibiting antigen-specific IgE production. | 1997 May 1 |
3 |
| 21 |
9151790 | T cell source of type 1 cytokines determines illness patterns in respiratory syncytial virus-infected mice. | 1997 May 1 |
1 |
| 22 |
9209457 | The anti-tumor effects of IL-12 involve enhanced IFN-gamma production by anti-tumor T cells, their accumulation to tumor sites and in situ IFN-gamma production. | 1997 Apr |
1 |
| 23 |
8568248 | IL-12 is essential for resistance against Yersinia enterocolitica by triggering IFN-gamma production in NK cells and CD4+ T cells. | 1996 Feb 15 |
2 |
| 24 |
8656046 | Interleukin-12 protects thermally injured mice from herpes simplex virus type 1 infection. | 1996 May |
2 |
| 25 |
8671675 | Molecular mechanisms underlying IFN-gamma-mediated tumor growth inhibition induced during tumor immunotherapy with rIL-12. | 1996 Jun |
1 |
| 26 |
8759743 | IL-12 is both required and sufficient for initiating T cell reactivity to a class I-restricted tumor peptide (P815AB) following transfer of P815AB-pulsed dendritic cells. | 1996 Aug 15 |
1 |
| 27 |
7636230 | The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro. | 1995 Aug 15 |
1 |
| 28 |
8527411 | Systemic administration of rIL-12 induces complete tumor regression and protective immunity: response is correlated with a striking reversal of suppressed IFN-gamma production by anti-tumor T cells. | 1995 Jul |
2 |
| 29 |
7909326 | Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. | 1994 May 1 |
1 |