| 1 |
34993951 | Children with atopic dermatitis show increased activity of β-glucocerebrosidase and stratum corneum levels of glucosylcholesterol that are strongly related to the local cytokine milieu. | 2022 Jun |
2 |
| 2 |
35401150 | Glucocerebrosidase Mutations Cause Mitochondrial and Lysosomal Dysfunction in Parkinson's Disease: Pathogenesis and Therapeutic Implications. | 2022 |
3 |
| 3 |
35637196 | GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway. | 2022 May 30 |
1 |
| 4 |
33219714 | The Role of Cholesterol in α-Synuclein and Lewy Body Pathology in GBA1 Parkinson's Disease. | 2021 May |
1 |
| 5 |
33604626 | Direct LC-ESI-MS/MS analysis of plant glucosylceramide and ceramide species with 8E and 8Z isomers of the long chain base. | 2021 Feb 18 |
1 |
| 6 |
33665756 | Acid Sphingomyelinase and Acid β-Glucosidase 1 Exert Opposite Effects on Interleukin-1β-Induced Interleukin 6 Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes. | 2021 Aug |
1 |
| 7 |
33684145 | β-Sitosterol 3-O-D-glucoside increases ceramide levels in the stratum corneum via the up-regulated expression of ceramide synthase-3 and glucosylceramide synthase in a reconstructed human epidermal keratinization model. | 2021 |
1 |
| 8 |
34720832 | A Japanese Patient with Gaucher Disease Treated with the Oral Drug Eliglustat as Substrate Reducing Therapy. | 2021 Sep-Dec |
1 |
| 9 |
32092464 | Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition. | 2020 Jun |
1 |
| 10 |
32265319 | Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities. | 2020 Jun |
4 |
| 11 |
33163670 | Enzyme kinetics and inhibition parameters of human leukocyte glucosylceramidase. | 2020 Nov |
2 |
| 12 |
30669468 | Selective Targeting of the Interconversion between Glucosylceramide and Ceramide by Scaffold Tailoring of Iminosugar Inhibitors. | 2019 Jan 19 |
1 |
| 13 |
29579237 | Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function. | 2018 Jun 1 |
2 |
| 14 |
29746165 | A lysosome-plasma membrane-sphingolipid axis linking lysosomal storage to cell growth arrest. | 2018 Oct |
1 |
| 15 |
29863755 | pH in nature, humans and skin. | 2018 Sep |
1 |
| 16 |
30300355 | Strawberry seed extract and its major component, tiliroside, promote ceramide synthesis in the stratum corneum of human epidermal equivalents. | 2018 |
1 |
| 17 |
28258214 | Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease. | 2017 Apr 14 |
1 |
| 18 |
28574511 | Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death. | 2017 Jul |
1 |
| 19 |
28763689 | Investigation of novel pharmacological chaperones for Gaucher Disease. | 2017 Sep |
2 |
| 20 |
28890071 | Serum lipid alterations in GBA-associated Parkinson's disease. | 2017 Nov |
1 |
| 21 |
29025868 | In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling. | 2017 Dec |
2 |
| 22 |
27098312 | Progress and potential of non-inhibitory small molecule chaperones for the treatment of Gaucher disease and its implications for Parkinson disease. | 2016 May |
1 |
| 23 |
25552189 | Increased glucocerebrosidase expression and activity in preeclamptic placenta. | 2015 Feb |
2 |
| 24 |
25933391 | Gene-wise association of variants in four lysosomal storage disorder genes in neuropathologically confirmed Lewy body disease. | 2015 |
1 |
| 25 |
26220345 | Lack of enzyme activity in GBA2 mutants associated with hereditary spastic paraplegia/cerebellar ataxia (SPG46). | 2015 Sep 11 |
1 |
| 26 |
26351046 | [Pathogenic mechanism and therapies for Gaucher's disease]. | 2015 Jun |
2 |
| 27 |
24477431 | Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease. | 2014 Mar |
1 |
| 28 |
23250757 | The non-lysosomal β-glucosidase GBA2 is a non-integral membrane-associated protein at the endoplasmic reticulum (ER) and Golgi. | 2013 Feb 1 |
1 |
| 29 |
24058461 | Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: a pilot study. | 2013 |
4 |
| 30 |
22451348 | A reconstructed human epidermal keratinization culture model to characterize ceramide metabolism in the stratum corneum. | 2012 Sep |
1 |
| 31 |
22884781 | Th1 cytokines accentuate but Th2 cytokines attenuate ceramide production in the stratum corneum of human epidermal equivalents: an implication for the disrupted barrier mechanism in atopic dermatitis. | 2012 Oct |
1 |
| 32 |
21235447 | Recent advances in treatment approaches to Gaucher disease. | 2011 Jun |
1 |
| 33 |
21384831 | Computational prediction of structure-activity relationships for the binding of aminocyclitols to β-glucocerebrosidase. | 2011 Mar 28 |
1 |
| 34 |
21982627 | Skin ultrastructural findings in type 2 Gaucher disease: diagnostic implications. | 2011 Dec |
1 |
| 35 |
19279008 | Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid. | 2009 May 8 |
7 |
| 36 |
19279011 | Involvement of acid beta-glucosidase 1 in the salvage pathway of ceramide formation. | 2009 May 8 |
7 |
| 37 |
19366370 | Sodium lauryl sulphate alters the mRNA expression of lipid-metabolizing enzymes and PPAR signalling in normal human skin in vivo. | 2009 Dec |
1 |
| 38 |
17803231 | An evolutionary and structure-based docking model for glucocerebrosidase-saposin C and glucocerebrosidase-substrate interactions - relevance for Gaucher disease. | 2008 Feb 15 |
1 |
| 39 |
15494128 | Measurement of lysosomal glucocerebrosidase activity in mouse liver using a fluorescence-activated cell sorter assay. | 2004 Nov 15 |
1 |
| 40 |
12554947 | Crystallization and preliminary X-ray analysis of recombinant human acid beta-glucocerebrosidase, a treatment for Gaucher's disease. | 2003 Feb |
1 |
| 41 |
10951276 | High-expression of sphingomyelin deacylase is an important determinant of ceramide deficiency leading to barrier disruption in atopic dermatitis. | 2000 Sep |
1 |
| 42 |
7817665 | Analysis of beta-glucocerebrosidase and ceramidase activities in atopic and aged dry skin. | 1994 Sep |
3 |
| 43 |
1431599 | beta-Glucocerebrosidase activity in murine epidermis: characterization and localization in relation to differentiation. | 1992 Aug |
1 |