| 1 |
35000550 | Assessment of drug-drug interactions of CC-90001, a potent and selective inhibitor of c-Jun N-terminal kinase. | 2021 Dec |
1 |
| 2 |
31177627 | Angiotensin II inhibits P-glycoprotein in intestinal epithelial cells. | 2020 Jan |
1 |
| 3 |
31540689 | Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs. | 2019 Nov 12 |
2 |
| 4 |
29709579 | New insights in the in vitro characterisation and molecular modelling of the P-glycoprotein inhibitory promiscuity. | 2018 Aug 30 |
1 |
| 5 |
30091221 | PBPK Models for CYP3A4 and P-gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin. | 2018 Oct |
1 |
| 6 |
30238965 | Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P-gp Inhibition. | 2018 Nov |
1 |
| 7 |
27557477 | Effect of proinflammatory cytokine IL-6 on efflux transport of rebamipide in Caco-2 cells. | 2017 Sep |
2 |
| 8 |
27452443 | The effect of 17α-ethynylestradiol induced intrahepatic cholestasis of pregnancy on placental P-glycoprotein in mice: Implications in the individualized transplacental digoxin treatment for fetal heart failure. | 2016 Aug |
1 |
| 9 |
27720954 | In-vitro investigation regarding the effects of Gelucire® 44/14 and Labrasol® ALF on the secretory intestinal transport of P-gp substrates. | 2016 Dec 30 |
1 |
| 10 |
26652279 | Transport of digoxin-loaded polymeric nanoparticles across BeWo cells, an in vitro model of human placental trophoblast. | 2015 |
2 |
| 11 |
24362330 | Phorbol 12-myristate 13-acetate inhibits P-glycoprotein-mediated efflux of digoxin in MDCKII-MDR1 and Caco-2 cell monolayer models. | 2014 Feb |
1 |
| 12 |
25172788 | Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza. | 2014 Sep 25 |
1 |
| 13 |
25342921 | Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug-drug interaction study. | 2014 |
1 |
| 14 |
23684934 | A P-gp vesicular transport inhibition assay - optimization and validation for drug-drug interaction testing. | 2013 Jul 16 |
1 |
| 15 |
23976943 | Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp. | 2013 |
8 |
| 16 |
23221528 | Effect of TSHAC on human cytochrome P450 activity, and transport mediated by P-glycoprotein. | 2012 Dec |
1 |
| 17 |
21162698 | Interactions between the chemotherapeutic agent eribulin mesylate (E7389) and P-glycoprotein in CF-1 abcb1a-deficient mice and Caco-2 cells. | 2011 Apr |
1 |
| 18 |
22028772 | Fitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithm. | 2011 |
2 |
| 19 |
20091240 | Effects of Acanthopanax senticosus HARMS extract on drug transport in human intestinal cell line Caco-2. | 2010 Jan |
1 |
| 20 |
20222053 | Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters. | 2010 Mar |
1 |
| 21 |
19414624 | Up-regulation of transporters and enzymes by the vitamin D receptor ligands, 1alpha,25-dihydroxyvitamin D3 and vitamin D analogs, in the Caco-2 cell monolayer. | 2009 Aug |
1 |
| 22 |
19082742 | P-gp inhibition potential in cell-based models: which "calculation" method is the most accurate? | 2008 Dec |
1 |
| 23 |
17377214 | Impact of ABCB1 (MDR1) gene polymorphism and P-glycoprotein inhibitors on digoxin serum concentration in congestive heart failure patients. | 2007 Jan-Feb |
2 |
| 24 |
17827785 | Efflux transport of N-monodesethylamiodarone by the human intestinal cell-line Caco-2 cells. | 2007 Aug |
1 |
| 25 |
16419049 | Effects of citronellal, a monoterpenoid in Zanthoxyli Fructus, on the intestinal absorption of digoxin in vitro and in vivo. | 2006 Mar |
2 |
| 26 |
16674925 | Effects of capsaicin on P-gp function and expression in Caco-2 cells. | 2006 Jun 14 |
1 |
| 27 |
16790532 | HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein. | 2006 Sep |
2 |
| 28 |
16964701 | [Is MDR 1 gene a key to successful chemotherapy?]. | 2006 Jun |
1 |
| 29 |
17063398 | Mechanisms responsible for poor oral bioavailability of paeoniflorin: Role of intestinal disposition and interactions with sinomenine. | 2006 Dec |
1 |
| 30 |
15890377 | Inhibition of P-glycoprotein-mediated transport by extracts of and monoterpenoids contained in Zanthoxyli fructus. | 2005 Dec 1 |
1 |
| 31 |
15207543 | Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery. | 2004 Jul |
1 |
| 32 |
14560928 | Commonly used surfactant, Tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats. | 2003 Sep |
1 |
| 33 |
12492608 | MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males. | 2002 Dec |
1 |
| 34 |
10213372 | Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. | 1999 Mar |
1 |
| 35 |
10463589 | P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies. | 1999 Aug 15 |
2 |
| 36 |
10742982 | Multidrug-resistance transporters. | 1999 |
1 |
| 37 |
1360207 | The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. | 1992 Nov 30 |
1 |