Cyclosporine

phosphoglycolate phosphatase ; Homo sapiens







73 Article(s)
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1 35623257 Laser-responsive multi-functional nanoparticles for efficient combinational chemo-photodynamic therapy against breast cancer. 2022 Aug 2
2 32810615 Dextran sulfate sodium-induced colitis and ginseng intervention altered oral pharmacokinetics of cyclosporine A in rats. 2021 Jan 30 2
3 33528601 Surface plasmon resonance biosensor combined with lentiviral particle stabilization strategy for rapid and specific screening of P-Glycoprotein ligands. 2021 Mar 2
4 32739890 A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach. 2020 Oct 1
5 32987693 Prediction of Cyclosporin-Mediated Drug Interaction Using Physiologically Based Pharmacokinetic Model Characterizing Interplay of Drug Transporters and Enzymes. 2020 Sep 24 2
6 30991038 Rifampin Induces Expression of P-glycoprotein on the THP1 Cell-Derived Macrophages, Causing Decrease Intramacrophage Concentration of Prothionamide. 2019 Sep 1
7 30335563 Dose Optimization Based on Population Pharmacokinetic Modeling of High-Dose Cyclosporine, a P-glycoprotein Inhibitor, in Combination with Systemic Chemotherapy in Pediatric Patients with Retinoblastoma. 2018 Nov 1
8 30388019 Gut Microbiota-Mediated Bile Acid Transformations Alter the Cellular Response to Multidrug Resistant Transporter Substrates in Vitro: Focus on P-glycoprotein. 2018 Dec 3 2
9 26961540 Identification of Transporters Involved in Beraprost Sodium Transport In Vitro. 2017 Feb 1
10 27557477 Effect of proinflammatory cytokine IL-6 on efflux transport of rebamipide in Caco-2 cells. 2017 Sep 1
11 28114946 Permeability across a novel microfluidic blood-tumor barrier model. 2017 Jan 23 1
12 28675836 Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer. 2017 Sep 29 1
13 26190674 A functional model for feline P-glycoprotein. 2016 Feb 2
14 25240837 Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation. 2014 Dec 2
15 25280976 Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children. 2014 Dec 2
16 25309926 18FDG, [18F]FLT, [18F]FAZA, and 11C-methionine are suitable tracers for the diagnosis and in vivo follow-up of the efficacy of chemotherapy by miniPET in both multidrug resistant and sensitive human gynecologic tumor xenografts. 2014 3
17 25505597 Characterization of a novel brain barrier ex vivo insect-based P-glycoprotein screening model. 2014 Aug 2
18 23593196 Screening compounds with a novel high-throughput ABCB1-mediated efflux assay identifies drugs with known therapeutic targets at risk for multidrug resistance interference. 2013 1
19 21631587 Sirolimus and everolimus intestinal absorption and interaction with calcineurin inhibitors: a differential effect between cyclosporine and tacrolimus. 2012 Aug 1
20 22615870 Small-molecule synthetic compound norcantharidin reverses multi-drug resistance by regulating Sonic hedgehog signaling in human breast cancer cells. 2012 1
21 22773077 Intestinal absorption of forsythoside A in in situ single-pass intestinal perfusion and in vitro Caco-2 cell models. 2012 Aug 1
22 21443601 Pharmacokinetic interactions between alitretinoin and ketoconazole or simvastatin or ciclosporin A. 2011 Apr 1
23 21725799 Validation of quinidine as a probe substrate for the in vitro P-gp inhibition assay in Caco-2 cell monolayer. 2011 Sep 1
24 20163160 Effect of HEPES buffer on the uptake and transport of P-glycoprotein substrates and large neutral amino acids. 2010 Apr 5 1
25 20505666 Donor P-gp polymorphisms strongly influence renal function and graft loss in a cohort of renal transplant recipients on cyclosporine therapy in a long-term follow-up. 2010 Jul 3
26 20662321 Interaction of CJZ3, a lomerizine derivative, with ATPase activity of human P-glycoprotein in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells. 2010 Jul 3
27 19423340 Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin. 2009 Jun 15 1
28 19589390 CJX1, an amlodipine derivative, interacts with ATPase of human P-glycoprotein. 2009 Oct 2
29 17936633 Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives. 2008 Jan 1 1
30 17940134 Oseltamivir (Tamiflu) efflux transport at the blood-brain barrier via P-glycoprotein. 2008 Jan 1
31 18594053 Corticosteroid interactions with cyclosporine, tacrolimus, mycophenolate, and sirolimus: fact or fiction? 2008 Jul 1
32 19356075 Influence of ABCB1 gene polymorphisms and P-glycoprotein activity on cyclosporine pharmacokinetics in peripheral blood mononuclear cells in healthy volunteers. 2008 Apr 3
33 17545536 A comparison of the pharmacokinetics and pharmacodynamics of docetaxel between African-American and Caucasian cancer patients: CALGB 9871. 2007 Jun 1 1
34 16466920 New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity. 2006 Jun 1 1
35 16522547 P-glycoprotein (P-170) expression in acute leukemias. 2006 Feb 2
36 16729976 Biochemical and pharmacological properties of an allosteric modulator site of the human P-glycoprotein (ABCB1). 2006 Jul 14 1
37 15661399 P-glycoprotein is implicated in the inhibition of ceramide-induced apoptosis in TF-1 acute myeloid leukemia cells by modulation of the glucosylceramide synthase pathway. 2005 Jan 1
38 15744065 Catfish egg lectin causes rapid activation of multidrug resistance 1 P-glycoprotein as a lipid translocase. 2005 Mar 2
39 16316932 Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport. 2005 Jul 1
40 15019079 Transport characteristics of 9-nitrocamptothecin in the human intestinal cell line Caco-2 and everted gut sacs. 2004 Mar 19 2
41 15289018 Addition of cyclosporin A to the combination of mitoxantrone and etoposide to overcome resistance to chemotherapy in refractory or relapsing acute myeloid leukaemia: a randomised phase II trial from HOVON, the Dutch-Belgian Haemato-Oncology Working Group for adults. 2004 Oct 2
42 12612437 Cyclosporine a augments P-glycoprotein expression in the regenerating rat liver. 2003 Mar 1
43 12848778 Frequency of C3435T single nucleotide MDR1 genetic polymorphism in an Asian population: phenotypic-genotypic correlates. 2003 Jul 1
44 12909621 Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein. 2003 Oct 10 1
45 11856485 Bromocriptine reverses P-glycoprotein-mediated multidrug resistance in tumor cells. 2002 Feb 2
46 11865967 Effect of calcineurin inhibitor therapy on P-gp expression and function in lymphocytes of renal transplant patients: a preliminary evaluation. 2002 Mar 1
47 11966513 P-glycoprotein-170 inhibition significantly reduces cortisol and ciclosporin efflux from human intestinal epithelial cells and T lymphocytes. 2002 May 4
48 12071854 Transport of phosphatidylserine via MDR1 (multidrug resistance 1)P-glycoprotein in a human gastric carcinoma cell line. 2002 Jul 1 2
49 12361387 Cyclosporins: structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC transporter. 2002 Oct 10 6
50 12434394 Kinetic characterization of secretory transport of a new ciprofloxacin derivative (CNV97100) across Caco-2 cell monolayers. 2002 Dec 2