| 1 |
33275773 | ABCB1/MDR1/P-gp employs an ATP-dependent twist-and-squeeze mechanism to export hydrophobic drugs. | 2021 Mar |
1 |
| 2 |
33918289 | NCX-4040, a Unique Nitric Oxide Donor, Induces Reversal of Drug-Resistance in Both ABCB1- and ABCG2-Expressing Multidrug Human Cancer Cells. | 2021 Apr 2 |
1 |
| 3 |
34350184 | Branebrutinib (BMS-986195), a Bruton's Tyrosine Kinase Inhibitor, Resensitizes P-Glycoprotein-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Agents. | 2021 |
1 |
| 4 |
31750987 | P-glycoprotein: a role in the export of amyloid-β in Alzheimer's disease? | 2020 Feb |
1 |
| 5 |
32479062 | Photoactivated H2 Nanogenerator for Enhanced Chemotherapy of Bladder Cancer. | 2020 Jul 28 |
1 |
| 6 |
33064007 | Nanoenabled Intracellular Calcium Bursting for Safe and Efficient Reversal of Drug Resistance in Tumor Cells. | 2020 Nov 11 |
1 |
| 7 |
33353070 | Computational Insights into Allosteric Conformational Modulation of P-Glycoprotein by Substrate and Inhibitor Binding. | 2020 Dec 18 |
1 |
| 8 |
31719828 | Developmental Roles of AUX1/LAX Auxin Influx Carriers in Plants. | 2019 |
1 |
| 9 |
29475007 | P-gp is involved in the intestinal absorption and biliary excretion of afatinib in vitro and in rats. | 2018 Apr |
1 |
| 10 |
30217571 | Role of the efflux transporters BCRP and MRP1 in human placental bio-disposition of pravastatin. | 2018 Oct |
1 |
| 11 |
30251669 | Nitric oxide reverses drug resistance by inhibiting ATPase activity of p-glycoprotein in human multi-drug resistant cancer cells. | 2018 Dec |
2 |
| 12 |
28826615 | Glycerol-3-phosphate phosphatase/PGP: Role in intermediary metabolism and target for cardiometabolic diseases. | 2017 Dec |
1 |
| 13 |
26755581 | Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytes. | 2016 Jan 26 |
1 |
| 14 |
27422165 | Spica prunellae and its marker compound rosmarinic acid induced the expression of efflux transporters through activation of Nrf2-mediated signaling pathway in HepG2 cells. | 2016 Dec 4 |
2 |
| 15 |
27514711 | Design and Synthesis of New Selective P-gp Substrates and Inhibitors. | 2016 |
1 |
| 16 |
29441851 | A myrsinol diterpene isolated from Euphorbia prolifera reverses multidrug resistance in breast cancer cells. | 2016 Sep 1 |
1 |
| 17 |
24993742 | MDR1 gene polymorphisms and P-glycoprotein expression in respiratory diseases. | 2015 Sep |
1 |
| 18 |
25644220 | TPGS2k/PLGA nanoparticles for overcoming multidrug resistance by interfering mitochondria of human alveolar adenocarcinoma cells. | 2015 Feb 25 |
1 |
| 19 |
24504599 | Frequency of MDR1-related p-gp overexpression in Greek Leishmania isolates. | 2014 Mar |
1 |
| 20 |
24624364 | Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function. | 2014 |
1 |
| 21 |
24769346 | Synthesis, cytotoxic study and docking based multidrug resistance modulator potential analysis of 2-(9-oxoacridin-10(9H)-yl)-N-phenyl acetamides. | 2014 Jun 10 |
1 |
| 22 |
24377601 | Knockdown of MDR1 increases the sensitivity to adriamycin in drug resistant gastric cancer cells. | 2013 |
1 |
| 23 |
22272278 | Efflux protein expression in human stem cell-derived retinal pigment epithelial cells. | 2012 |
2 |
| 24 |
22445254 | Poly(caprolactone)-modified Pluronic P105 micelles for reversal of paclitaxcel-resistance in SKOV-3 tumors. | 2012 Jun |
1 |
| 25 |
22632934 | Click chemistry-derived bivalent quinine inhibitors of P-glycoprotein-mediated cellular efflux. | 2012 Jul 1 |
1 |
| 26 |
22647192 | Catalytic transitions in the human MDR1 P-glycoprotein drug binding sites. | 2012 Jun 26 |
1 |
| 27 |
21392495 | First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line. | 2011 May |
1 |
| 28 |
22028772 | Fitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithm. | 2011 |
3 |
| 29 |
22163059 | Genetic knockdown and pharmacological inhibition of parasite multidrug resistance transporters disrupts egg production in Schistosoma mansoni. | 2011 Dec |
1 |
| 30 |
22174631 | Tunicamycin depresses P-glycoprotein glycosylation without an effect on its membrane localization and drug efflux activity in L1210 cells. | 2011 |
1 |
| 31 |
20053485 | Synthesis of highly functionalized barbituric acids and study of their interactions with p-glycoprotein and Mg2+--potential candidates for multi drug resistance modulation. | 2010 Mar |
1 |
| 32 |
20645921 | N,N-bis(cyclohexanol)amine aryl esters: the discovery of a new class of highly potent inhibitors of transporter-dependent multidrug resistance (MDR). | 2010 |
1 |
| 33 |
18955135 | A 3D linear solvation energy model to quantify the affinity of flavonoid derivatives toward P-glycoprotein. | 2009 Feb 15 |
1 |
| 34 |
19397308 | Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments. | 2009 Nov-Dec |
1 |
| 35 |
19591810 | Opiates inhibit paclitaxel uptake by P-glycoprotein in preparations of human placental inside-out vesicles. | 2009 Nov 1 |
1 |
| 36 |
19762091 | Is resistance useless? Multidrug resistance and collateral sensitivity. | 2009 Oct |
1 |
| 37 |
18633246 | [Vinca alkaloid and MDR1]. | 2008 Jul |
2 |
| 38 |
18723777 | A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport. | 2008 Nov |
1 |
| 39 |
17095178 | Conformational mobility of immobilized proteins. | 2007 Jan 17 |
1 |
| 40 |
17524504 | The small GTPases Rab5 and RalA regulate intracellular traffic of P-glycoprotein. | 2007 Jul |
1 |
| 41 |
23100919 | Multidrug resistance 1 gene expression and AgNOR in childhood acute leukemias. | 2007 Dec |
1 |
| 42 |
16439618 | Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana. | 2006 May |
1 |
| 43 |
17142983 | Evaluation of human P-glycoprotein (MDR1/ABCB1) ATPase activity assay method by comparing with in vitro transport measurements: Michaelis-Menten kinetic analysis to estimate the affinity of P-glycoprotein to drugs. | 2006 Dec |
1 |
| 44 |
17215888 | P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors. | 2006 Dec |
2 |
| 45 |
16229490 | Nucleotide binding to the multidrug resistance P-glycoprotein as studied by ESR spectroscopy. | 2005 Oct 25 |
2 |
| 46 |
14999785 | Disruption of P-glycoprotein anticancer drug efflux activity by a small recombinant single-chain Fv antibody fragment targeted to an extracellular epitope. | 2004 May 1 |
1 |
| 47 |
15180339 | Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines. | 2004 May |
1 |
| 48 |
16028354 | Disulfiram metabolites permanently inactivate the human multidrug resistance P-glycoprotein. | 2004 Nov-Dec |
1 |
| 49 |
12421806 | Drug binding in human P-glycoprotein causes conformational changes in both nucleotide-binding domains. | 2003 Jan 17 |
1 |
| 50 |
12551908 | Three-dimensional reconstruction of the Saccharomyces cerevisiae multidrug resistance protein Pdr5p. | 2003 Apr 4 |
1 |