Fluorouracil

proteasome 26S subunit, non-ATPase 1 ; Homo sapiens







133 Article(s)
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1 32377978 Phase I study of DFP-11207, a novel oral fluoropyrimidine with reasonable AUC and low Cmax and improved tolerability, in patients with solid tumors. 2020 Dec 2
2 32774071 Transarterial chemoembolization with hepatic arterial infusion chemotherapy plus S-1 for hepatocellular carcinoma. 2020 Jul 21 1
3 31011915 Pharmacokinetics of S-1 monotherapy in plasma and in tears for gastric cancer patients. 2019 Jun 2
4 31310349 Histopathological changes in tumor budding between biopsy and resected specimens from patients treated with preoperative S-1 chemotherapy for oral cancer. 2019 Nov 2
5 28554183 A Pilot Trial of S-1 and Paclitaxel in Unresectable or Postoperative Recurrent Esophageal Squamous Cell Carcinoma Pretreated by Fluorouracil, Cisplatin, and Docetaxel Chemotherapy. 2018 3
6 29362333 [Chemoradiotherapy with S-1 for Recurrence Cases of Colorectal Cancer]. 2018 Jan 1
7 29931401 Determination of 5-fluorouracil and tegafur in tear fluid of patients treated with oral fluoropyrimidine anticancer agent, S-1. 2018 Jul 4
8 29945701 [Efficacy of S-1 in Advanced Non-small Cell Lung Cancer Patients Treated 
with More Than Two Lines of Chemotherapy]. 2018 Jun 20 1
9 26715117 Associations between CYP2A6 polymorphisms and outcomes of adjuvant S-1 chemotherapy in patients with curatively resected gastric cancer. 2017 Jan 1
10 27643822 New Perspectives in the Treatment of Advanced Gastric Cancer: S-1 as a Novel Oral 5-FU Therapy in Combination with Cisplatin. 2017 3
11 28159957 Pharmacokinetics of initial full and subsequent reduced doses of S-1 in patients with locally advanced head and neck cancer-effect of renal insufficiency. 2017 May 1 3
12 28497756 S-1 versus placebo in patients with sorafenib-refractory advanced hepatocellular carcinoma (S-CUBE): a randomised, double-blind, multicentre, phase 3 trial. 2017 Jun 1
13 29045553 Randomized controlled trial of S-1 versus docetaxel in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy (East Asia S-1 Trial in Lung Cancer). 2017 Nov 1 1
14 29137320 A phase II study of S-1 with concurrent radiotherapy in elderly patients with esophageal cancer. 2017 Oct 10 1
15 26811188 S-1-based regimens and the risk of leucopenic complications; a Meta-analysis with comparison to other fluoropyrimidines and non fluoropyrimidines. 2016 1
16 27076940 A phase I dose escalation study of S-1 with concurrent radiotherapy in elderly patients with esophageal cancer. 2016 Mar 1
17 29874335 S-1 monotherapy as second line chemotherapy in advanced gastric cancer patients previously treated with cisplatin/infusional fluorouracil [Retraction]. 2016 1
18 25423960 HPV Status Determines the Efficacy of Adjuvant Chemotherapy With S-1, an Oral Fluorouracil Prodrug, in Oropharyngeal Cancer. 2015 May 2
19 25707610 Clinical Benefit and Health-Related Quality of Life Assessment in Patients Treated with Cisplatin/S-1 Versus Cisplatin/5-FU: Secondary End Point Results From the First-Line Advanced Gastric Cancer Study (FLAGS). 2015 Jun 1
20 25756340 Corneal limbal stem cell deficiency associated with the anticancer drug S-1. 2015 Apr 1
21 25810324 Postgastrectomy pharmacokinetic changes of S-1 in patients with localized advanced gastric cancer. 2015 Aug 1
22 25932284 Phase II multi-center clinical study on using S-1 to treat advanced breast cancer after resistance to anthracycline and taxane drugs in Chinese patients. 2015 1
23 26025485 Phase I study of postoperative radiotherapy concurrent with S-1 in patients with gastric cancer. 2015 Jul 1
24 26220845 S-1 and irinotecan with or without bevacizumab versus 5-fluorouracil and leucovorin plus oxaliplatin with or without bevacizumab in metastatic colorectal cancer: a pooled analysis of four phase II studies. 2015 Sep 2
25 26811591 Emerging role of S-1 in gastric cancer. 2015 Oct-Dec 1
26 25031751 S-1 monotherapy as second line chemotherapy in advanced gastric cancer patients previously treated with cisplatin/infusional fluorouracil. 2014 3
27 25120809 S-1 monotherapy as second line chemotherapy in advanced gastric cancer patients previously treated with cisplatin/infusional fluorouracil. 2014 3
28 25140293 Synergistic antitumor effects of S-1 with eribulin in vitro and in vivo for triple-negative breast cancer cell lines. 2014 1
29 25386059 S-1 in the treatment of pancreatic cancer. 2014 Nov 7 4
30 23719766 S-1 (Teysuno®): a review of its use in advanced gastric cancer in non-Asian populations. 2013 Jun 2
31 23761814 High efficacy of combination chemotherapy with S-1 and low-dose docetaxel for the treatment of highly advanced gastric cancer with peritoneal dissemination: A case report. 2013 May 1
32 23963147 S-1 plus irinotecan and oxaliplatin for the first-line treatment of patients with metastatic colorectal cancer: a prospective phase II study and pharmacogenetic analysis. 2013 Sep 17 1
33 23982118 Phase I clinical and pharmacokinetic/pharmacogenetic study of a triplet regimen of S-1/irinotecan/oxaliplatin in patients with metastatic colorectal or gastric cancer. 2013 Nov 1
34 24047774 [Phase I study of sequential S-1 and cyclophosphamide therapy in patients with metastatic breast cancer]. 2013 Sep 1
35 24156021 Therapeutic enhancement of S-1 with CPT-11 through down-regulation of thymidylate synthase in bladder cancer. 2013 Aug 1
36 21351099 Low-dose docetaxel enhances the sensitivity of S-1 in a xenograft model of human castration resistant prostate cancer. 2012 Jan 15 2
37 22235991 S-1 as a core anticancer fluoropyrimidine agent. 2012 Mar 2
38 22322240 Characteristic CYP2A6 genetic polymorphisms detected by TA cloning-based sequencing in Chinese digestive system cancer patients with S-1 based chemotherapy. 2012 May 2
39 22353201 Pharmacokinetic study of weekly (days 1-5) low-dose S-1 in patients with non-small-cell lung cancer. 2012 May 1
40 22424872 A multicenter phase II study of adjuvant chemotherapy with oral fluoropyrimidine S-1 for non-small-cell lung cancer: high completion and survival rates. 2012 Nov 1
41 22740861 Sequential irinotecan hydrochloride/S-1 for S-1-resistant inoperable gastric cancer: A feasibility study. 2012 Jan 1
42 22960985 Phase II tailored S-1 regimen study of first-line chemotherapy in elderly patients with advanced and recurrent non-small cell lung cancer. 2012 Dec 2
43 23033004 Phase I/II trial of a biweekly combination of S-1 plus docetaxel in patients with previously treated non-small cell lung cancer (KRSG-0601). 2012 Oct 23 1
44 23291139 [A phase II prospective randomized controlled trial of weekly paclitaxel combined with S-1 or fluorouracil for advanced gastric carcinoma]. 2012 Nov 1
45 20451285 A phase I study of S-1 with concurrent thoracic radiotherapy in elderly patients with localized advanced non-small cell lung cancer. 2011 Jan 1
46 20714726 A phase II and pharmacokinetic study of first line S-1 for advanced gastric cancer in Taiwan. 2011 Jun 1
47 21079960 The therapeutic efficacy of S-1 against orthotopically implanted human pleural mesothelioma cells in severe combined immunodeficient mice. 2011 Aug 2
48 21143703 Comparison of the pharmacokinetics and pharmacodynamics of S-1 between Caucasian and East Asian patients. 2011 Feb 2
49 21273614 Successful S-1 monotherapy for chemorefractory thymic carcinoma. 2011 Jan 1
50 21326246 Phase II study of S-1 combined with oxaliplatin as therapy for patients with metastatic biliary tract cancer: influence of the CYP2A6 polymorphism on pharmacokinetics and clinical activity. 2011 Feb 15 1