Ketones

3-hydroxy-3-methylglutaryl-CoA synthase 2 ; Homo sapiens







12 Article(s)
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Title
Pub. Year
#Total Relationships
1 34624592 Epigenetic inactivation of hydroxymethylglutaryl CoA synthase reduces ketogenesis and facilitates tumor cell motility in clear cell renal carcinoma. 2021 Nov 1
2 32635582 Loss of HMGCS2 Enhances Lipogenesis and Attenuates the Protective Effect of the Ketogenic Diet in Liver Cancer. 2020 Jul 4 1
3 31442404 Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. 2019 Aug 22 2
4 31779269 HMGCS2 Mediates Ketone Production and Regulates the Proliferation and Metastasis of Hepatocellular Carcinoma. 2019 Nov 26 5
5 30322448 Recurrent loss of HMGCS2 shows that ketogenesis is not essential for the evolution of large mammalian brains. 2018 Oct 16 1
6 28320515 HMGCS2 promotes autophagic degradation of the amyloid-β precursor protein through ketone body-mediated mechanisms. 2017 Apr 29 2
7 28512002 Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer. 2017 Aug 1
8 21952825 Characterization of splice variants of the genes encoding human mitochondrial HMG-CoA lyase and HMG-CoA synthase, the main enzymes of the ketogenesis pathway. 2012 Apr 2
9 23082721 Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells. 2012 Nov 1 1
10 23082722 Ketone body utilization drives tumor growth and metastasis. 2012 Nov 1 2
11 21502324 Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line. 2011 Jun 10 2
12 16940161 Ketogenic HMGCS2 Is a c-Myc target gene expressed in differentiated cells of human colonic epithelium and down-regulated in colon cancer. 2006 Sep 1