| 1 |
33648564 | Diabetes, obesity, and insulin resistance in COVID-19: molecular interrelationship and therapeutic implications. | 2021 Mar 1 |
2 |
| 2 |
33911136 | PKR activity modulation by phosphomimetic mutations of serine residues located three aminoacids upstream of double-stranded RNA binding motifs. | 2021 Apr 28 |
4 |
| 3 |
33921888 | Structure and Activities of the NS1 Influenza Protein and Progress in the Development of Small-Molecule Drugs. | 2021 Apr 19 |
1 |
| 4 |
34216619 | STING-mediated degradation of IFI16 negatively regulates apoptosis by inhibiting p53 phosphorylation at serine 392. | 2021 Aug |
2 |
| 5 |
34630117 | Targeting the Integrated Stress Response in Cancer Therapy. | 2021 |
1 |
| 6 |
29792216 | HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription. | 2018 May 23 |
2 |
| 7 |
28374749 | PKR activation and eIF2α phosphorylation mediate human globin mRNA splicing at spliceosome assembly. | 2017 May |
1 |
| 8 |
26698173 | Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE. | 2016 Feb 5 |
1 |
| 9 |
25653431 | p53-derived host restriction of HIV-1 replication by protein kinase R-mediated Tat phosphorylation and inactivation. | 2015 Apr |
1 |
| 10 |
23349666 | Phosphorylation of STAT-1 serine 727 is prolonged in HLA-B27-expressing human monocytic cells. | 2013 |
1 |
| 11 |
23519983 | Modulation of double-stranded RNA-activated protein kinase in insulin sensitive tissues of obese humans. | 2013 Dec |
1 |
| 12 |
23597922 | STAT1 requirement for PKR-induced cell cycle arrest in vascular smooth muscle cells in response to heparin. | 2013 Jul 15 |
2 |
| 13 |
22355110 | PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium. | 2012 Mar 6 |
1 |
| 14 |
22473766 | Increased interaction between PACT molecules in response to stress signals is required for PKR activation. | 2012 Aug |
1 |
| 15 |
23259068 | PKCδ Regulates Translation Initiation through PKR and eIF2α in Response to Retinoic Acid in Acute Myeloid Leukemia Cells. | 2012 |
1 |
| 16 |
21320352 | Envelope 2 protein phosphorylation sites S75 & 277 of hepatitis C virus genotype 1a and interferon resistance: a sequence alignment approach. | 2011 Feb 15 |
2 |
| 17 |
21526770 | Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation. | 2011 May 31 |
1 |
| 18 |
20171114 | A role for protein kinase PKR in the mediation of Epstein-Barr virus latent membrane protein-1-induced IL-6 and IL-10 expression. | 2010 May |
2 |
| 19 |
19580324 | Biochemical analysis of PKR activation by PACT. | 2009 Aug 11 |
3 |
| 20 |
18096616 | Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR. | 2008 Feb |
2 |
| 21 |
18835251 | Nck-1 interacts with PKR and modulates its activation by dsRNA. | 2008 Dec 5 |
1 |
| 22 |
18957415 | PKR regulates B56(alpha)-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cells. | 2008 Dec 19 |
3 |
| 23 |
18971339 | Protein kinase PKR mutants resistant to the poxvirus pseudosubstrate K3L protein. | 2008 Nov 4 |
1 |
| 24 |
16516295 | IFN-gamma-induced upregulation of Fcgamma-receptor-I during activation of monocytic cells requires the PKR and NFkappaB pathways. | 2007 Jan |
2 |
| 25 |
17404396 | Involvement of ERKs, RSK2 and PKR in UVA-induced signal transduction toward phosphorylation of eIF2alpha (Ser(51)). | 2007 Jul |
2 |
| 26 |
16982605 | Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis. | 2006 Nov 17 |
2 |
| 27 |
15737233 | Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription. | 2005 Feb 28 |
2 |
| 28 |
15299031 | Serine 18 phosphorylation of RAX, the PKR activator, is required for PKR activation and consequent translation inhibition. | 2004 Oct 8 |
3 |
| 29 |
11756670 | Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. | 2002 Jan 8 |
1 |
| 30 |
12060652 | The double-stranded RNA-activated kinase, PKR, can phosphorylate hepatitis D virus small delta antigen at functional serine and threonine residues. | 2002 Sep 6 |
3 |
| 31 |
11152499 | Hepatitis C virus envelope protein E2 does not inhibit PKR by simple competition with autophosphorylation sites in the RNA-binding domain. | 2001 Feb |
4 |
| 32 |
10723127 | Activation of NF-kappa B by the dsRNA-dependent protein kinase, PKR involves the I kappa B kinase complex. | 2000 Mar 9 |
1 |
| 33 |
11040133 | Pseudosubstrate inhibition of protein kinase PKR by swine pox virus C8L gene product. | 2000 Oct 25 |
1 |
| 34 |
10348343 | The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro. | 1999 Apr 29 |
1 |
| 35 |
10373514 | Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB. | 1999 Jul |
4 |
| 36 |
10432301 | Caspase-mediated cleavage of eukaryotic translation initiation factor subunit 2alpha. | 1999 Aug 15 |
1 |
| 37 |
10542257 | The interferon-induced double-stranded RNA-activated protein kinase PKR will phosphorylate serine, threonine, or tyrosine at residue 51 in eukaryotic initiation factor 2alpha. | 1999 Nov 5 |
2 |
| 38 |
9079663 | The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR. | 1997 Mar 28 |
1 |
| 39 |
9199350 | Regulation of the protein kinase PKR by the vaccinia virus pseudosubstrate inhibitor K3L is dependent on residues conserved between the K3L protein and the PKR substrate eIF2alpha. | 1997 Jul |
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