Poly I-C

eukaryotic translation initiation factor 2 alpha kinase 2 ; Homo sapiens







18 Article(s)
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1 33459340 Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling. 2021 Feb 12 1
2 33911136 PKR activity modulation by phosphomimetic mutations of serine residues located three aminoacids upstream of double-stranded RNA binding motifs. 2021 Apr 28 1
3 28266737 Epidermal keratinocytes sense dsRNA via the NLRP3 inflammasome, mediating interleukin (IL)-1β and IL-18 release. 2017 Oct 2
4 28445962 PSMA-homing dsRNA chimeric protein vector kills prostate cancer cells and activates anti-tumor bystander responses. 2017 Apr 11 1
5 27066702 Downregulation of protein kinase PKR activation by porcine reproductive and respiratory syndrome virus at its early stage infection. 2016 May 1 2
6 25797046 PCNA-interacting peptides reduce Akt phosphorylation and TLR-mediated cytokine secretion suggesting a role of PCNA in cellular signaling. 2015 Jul 2
7 23441162 HLA-B35 and dsRNA induce endothelin-1 via activation of ATF4 in human microvascular endothelial cells. 2013 2
8 23892079 IRF3 and ERK MAP-kinases control nitric oxide production from macrophages in response to poly-I:C. 2013 Sep 17 1
9 21861882 Differential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells. 2011 Aug 23 1
10 19028691 The RNA-activated protein kinase enhances the induction of interferon-beta and apoptosis mediated by cytoplasmic RNA sensors. 2009 Jan 16 2
11 17928888 IFN-alpha enhances poly-IC responses in human keratinocytes by inducing expression of cytosolic innate RNA receptors: relevance for psoriasis. 2008 Apr 2
12 17541283 Role of RIG-I, MDA-5, and PKR on the expression of inflammatory chemokines induced by synthetic dsRNA in airway epithelial cells. 2007 1
13 17142740 Innate cytokine responses in porcine macrophage populations: evidence for differential recognition of double-stranded RNA. 2006 Dec 15 1
14 15879132 Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus. 2005 May 15 8
15 15229216 Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation. 2004 Sep 3 2
16 10723127 Activation of NF-kappa B by the dsRNA-dependent protein kinase, PKR involves the I kappa B kinase complex. 2000 Mar 9 1
17 10823866 Expression of hepatitis C virus proteins interferes with the antiviral action of interferon independently of PKR-mediated control of protein synthesis. 2000 Jun 1
18 8806499 Peptides derived from the interferon-induced PKR prevent activation by HIV-1 TAR RNA. 1996 Aug 1 1