Dihydrotestosterone

hydroxysteroid 17-beta dehydrogenase 1 ; Homo sapiens







21 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 28554725 Substrate inhibition of 17β-HSD1 in living cells and regulation of 17β-HSD7 by 17β-HSD1 knockdown. 2017 Sep 1
2 28977936 The regulation of hydroxysteroid 17β-dehydrogenase type 1 and 2 gene expression in breast cancer cell lines by estradiol, dihydrotestosterone, microRNAs, and genes related to breast cancer. 2017 Sep 22 1
3 25257817 Reductive 17beta-hydroxysteroid dehydrogenases which synthesize estradiol and inactivate dihydrotestosterone constitute major and concerted players in ER+ breast cancer cells. 2015 Jun 1
4 24434280 Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity. 2014 May 1
5 24787657 Understanding androgen action in adipose tissue. 2014 Sep 1
6 23647539 A challenge for medicinal chemistry by the 17β-hydroxysteroid dehydrogenase superfamily: an integrated biological function and inhibition study. 2013 2
7 20172961 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. 2010 Apr 9
8 19038308 Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: critical in the cell proliferation of breast cancer. 2009 Mar 25 4
9 15862963 Cloning and characterization of human form 2 type 7 17beta-hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme. 2005 Feb 2
10 15882060 Mapping of steroids binding to 17 beta-hydroxysteroid dehydrogenase type 1 using Monte Carlo energy minimization reveals alternative binding modes. 2005 May 17 1
11 15666817 Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium. 2004 Nov 2
12 12490543 Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase. 2003 Feb 6
13 11165020 Inhibitors of type II 17beta-hydroxysteroid dehydrogenase. 2001 Jan 22 2
14 11336660 Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction. 2001 May 15 2
15 11711113 Modulatory effects of indomethacin on androgen metabolism in human gingival and oral periosteal fibroblasts. 2001 Dec 1
16 10625652 Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain. 2000 Jan 14 3
17 10419021 3D-structure of human estrogenic 17beta-HSD1: binding with various steroids. 1999 Apr-Jun 1
18 10428369 Spironolactone-related inhibitors of type II 17beta-hydroxysteroid dehydrogenase: chemical synthesis, receptor binding affinities, and proliferative/antiproliferative activities. 1999 Jun 1
19 7546291 The human type II 17 beta-hydroxysteroid dehydrogenase gene encodes two alternatively spliced mRNA species. 1995 Oct 1
20 7759109 Mapping of the HSD17B2 gene encoding type II 17 beta-hydroxysteroid dehydrogenase close to D16S422 on chromosome 16q24.1-q24.2. 1995 Feb 10 1
21 8380373 Androgen receptor-mediated stimulation of 17 beta-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. 1993 Jan 1